Martha Campbell-Thompson

Pancreatic adenocarcinoma patients with localised chronic severe pancreatitis show an increased number of single beta cells, without alterations in fractional insulin area.

Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.

Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell adhesion proteins in human uterine RL95-2 cells.

Intramuscular administration of recombinant adeno-associated virus 2 alpha-1 antitrypsin (rAAV-SERPINA1) vectors in a nonhuman primate model: safety and immunologic aspects.

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.

Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.

Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse.

Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon.

Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors.

Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway.

Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts.

Efficient hepatic delivery and expression from a recombinant adeno-associated virus 8 pseudotyped alpha1-antitrypsin vector.

Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system.

Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector.

Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice.

Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury.

Noninvasive imaging of islet grafts using positron-emission tomography.

Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy.

Alpha1-antitrypsin protects beta-cells from apoptosis.

Preclinical characterization of a recombinant adeno-associated virus type 1-pseudotyped vector demonstrates dose-dependent injection site inflammation and dissemination of vector genomes to distant sites.

In vitro studies of steroid hormones in neurofibromatosis 1 tumors and Schwann cells.

Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats.

In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA.

Distinct expression and activity profiles of largemouth bass (Micropterus salmoides) estrogen receptors in response to estradiol and nonylphenol.

Gene delivery to intestinal epithelial cells in vitro and in vivo with recombinant adeno-associated virus types 1, 2 and 5.

p53 regulates FAK expression in human tumor cells.

Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene.

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.

Biochemical correction of short-chain acyl-coenzyme A dehydrogenase deficiency after portal vein injection of rAAV8-SCAD.

The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy.

Recombinant adeno-associated virus-mediated gene delivery of long chain acyl coenzyme A dehydrogenase (LCAD) into LCAD-deficient mice.

Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery.

Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse.

Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency.

Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area.

Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice.

Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses.

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.

Combination of alpha-1 antitrypsin and doxycycline suppresses collagen-induced arthritis.

Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice.

Gel-mediated delivery of AAV1 vectors corrects ventilatory function in Pompe mice with established disease.

Adeno-associated virus-mediated correction of a canine model of glycogen storage disease type Ia.

Endothelial von Willebrand factor release due to eNOS deficiency predisposes to thrombotic microangiopathy in mouse aging kidney.

Diabetic eNOS-knockout mice develop accelerated retinopathy.

The pancreas in human type 1 diabetes.

Ex vivo transduction and transplantation of bone marrow cells for liver gene delivery of alpha1-antitrypsin.

N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance.

Analysis of steroid hormone effects on xenografted human NF1 tumor schwann cells.

Glycogen storage disease type Ia in canines: a model for human metabolic and genetic liver disease.

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model.

Selective stimulation of VEGFR2 accelerates progressive renal disease.

Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology.

Salivary PYY: a putative bypass to satiety.

Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes.

Pancreas organ weight in individuals with disease-associated autoantibodies at risk for type 1 diabetes.

Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors.

Increased complement activation in human type 1 diabetes pancreata.

Response to comments on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604.

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.

The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings.

New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation.

Organ donor specimens: What can they tell us about type 1 diabetes?

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.

A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice.

Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes.

Abnormalities of the Exocrine Pancreas in Type 1 Diabetes.

The influence of type 1 diabetes on pancreatic weight.

Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.

Pancreatic duct hyperplasia/dysplasia in type 1 diabetes and pancreatic weight in individuals with and without diabetes. Reply to Kobayashi T, Aida K, Fukui T et al [letter] and Saisho Y [letter].

Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells.

Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets.

Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.

Diagnostic Dilemma: Clinical and Histological Abnormalities in a Hispanic Patient With Diabetes.

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Islet-derived CD4 T-cells targeting proinsulin in human autoimmune diabetes.

Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.

Factors That Influence the Quality of RNA From the Pancreas of Organ Donors.

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?

Serum Trypsinogen Levels in Type 1 Diabetes.

5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency.

Insulitis in Autoantibody-Positive Pancreatic Donor With History of Gestational Diabetes Mellitus.

High Illicit Drug Abuse and Suicide in Organ Donors With Type 1 Diabetes.

Immunohistochemistry Staining for Human Alpha-1 Antitrypsin.

Periodic Acid-Schiff Staining with Diastase.

Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.

Response to Comment on Jackson et al. Insulitis in Autoantibody-Positive Pancreatic Donor With History of Gestational Diabetes Mellitus. Diabetes Care 2017;40:723-725.

Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA.