Yosuke Hirotsu

Genetic basis of a common tumor origin in the development of pancreatic mixed acinar-neuroendocrine-ductal carcinoma: A case report.

Detection of tumor-derived DNA dispersed in the airway improves the diagnostic accuracy of bronchoscopy for lung cancer.

Combined annotation-dependent depletion score for BRCA1/2 variants in patients with breast and/or ovarian cancer.

Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.

Analysis of tumor-derived DNA in plasma and bone marrow fluid in lung cancer patients.

Comparison between two amplicon-based sequencing panels of different scales in the detection of somatic mutations associated with gastric cancer.

Intrinsic HER2 V777L mutation mediates resistance to trastuzumab in a breast cancer patient.

Stepwise addition of genetic changes correlated with histological change from "well-differentiated" to "sarcomatoid" phenotypes: a case report.

Analysis of significantly mutated genes as a clinical tool for the diagnosis in a case of lung cancer.

Mutational analysis of multiple lung cancers: Discrimination between primary and metastatic lung cancers by genomic profile.

Elucidation of radiation-resistant clones by a serial study of intratumor heterogeneity before and after stereotactic radiotherapy in lung cancer.

Distribution of circulating tumor DNA in lung cancer: analysis of the primary lung and bone marrow along with the pulmonary venous and peripheral blood.

Very early response of circulating tumour-derived DNA in plasma predicts efficacy of nivolumab treatment in patients with non-small cell lung cancer.

Simultaneous detection of genetic and copy number alterations ingenes.

New therapeutic targets for pulmonary sarcomatoid carcinomas based on their genomic and phylogenetic profiles.