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Department of Physiology and Biophysics
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Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes.
Biophysical journal Jun, 2006 | Pubmed ID: 16565048
The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis.
The Journal of biological chemistry Jun, 2006 | Pubmed ID: 16603547
The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis.
Journal of cell science Aug, 2007 | Pubmed ID: 17666431
Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells.
Journal of cellular physiology Jul, 2008 | Pubmed ID: 18247359
MG53 nucleates assembly of cell membrane repair machinery.
Nature cell biology Jan, 2009 | Pubmed ID: 19043407
The amino-terminal peptide of Bax perturbs intracellular Ca2+ homeostasis to enhance apoptosis in prostate cancer cells.
American journal of physiology. Cell physiology Feb, 2009 | Pubmed ID: 19091958
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Nature May, 2009 | Pubmed ID: 19387438
Cardioprotection of ischemia/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair.
Circulation research Jul, 2010 | Pubmed ID: 20466981
Ca2+ overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle.
The Journal of biological chemistry Nov, 2010 | Pubmed ID: 20858894
Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21343302
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.
Journal of neuropathology and experimental neurology Apr, 2011 | Pubmed ID: 21412170
Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.
EMBO reports May, 2011 | Pubmed ID: 21475249
Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2012 | Pubmed ID: 22253476
Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in δ-Sarcoglycan-deficient Hamsters.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2012 | Pubmed ID: 22314291
Robert Wood Johnson Medical School
Noah Weisleder1,
Peihui Lin1,
Xiaoli Zhao1,
Matthew Orange1,
Hua Zhu1,
Jianjie Ma1
1Department of Physiology and Biophysics, Robert Wood Johnson Medical School
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