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Department of Surgery
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Hypothermia and valproic acid activate prosurvival pathways after hemorrhage.
The Journal of surgical research Jun, 2015 | Pubmed ID: 25777823
Addition of low-dose valproic acid to saline resuscitation provides neuroprotection and improves long-term outcomes in a large animal model of combined traumatic brain injury and hemorrhagic shock.
The journal of trauma and acute care surgery Dec, 2015 | Pubmed ID: 26680134
Resuscitation with Lyophilized Plasma Is Safe and Improves Neurological Recovery in a Long-Term Survival Model of Swine Subjected to Traumatic Brain Injury, Hemorrhagic Shock, and Polytrauma.
Journal of neurotrauma Jul, 2017 | Pubmed ID: 28228060
Valproic acid decreases brain lesion size and improves neurologic recovery in swine subjected to traumatic brain injury, hemorrhagic shock, and polytrauma.
The journal of trauma and acute care surgery Dec, 2017 | Pubmed ID: 28697014
Valproic acid induces prosurvival transcriptomic changes in swine subjected to traumatic injury and hemorrhagic shock.
The journal of trauma and acute care surgery Apr, 2018 | Pubmed ID: 29251706
Mesenchymal Stem Cell-Derived Exosomes Provide Neuroprotection and Improve Long-Term Neurologic Outcomes in a Swine Model of Traumatic Brain Injury and Hemorrhagic Shock.
Journal of neurotrauma Jul, 2018 | Pubmed ID: 29690826
University of Michigan
Aaron M. Williams*,1,
Umar F. Bhatti*,1,
Isabel S. Dennahy1,
Kiril Chtraklin1,
Panpan Chang1,
Nathan J. Graham1,
Basil M. Baccouche1,
Shalini Roy1,
Mohammed Harajli1,
Jing Zhou1,
Vahagn C. Nikolian1,
Qiufang Deng1,
Yuzi Tian1,
Baoling Liu1,
Yongqing Li1,
Gregory L. Hays1,2,
Julia L. Hays1,2,
Hasan B. Alam1
1Department of Surgery, University of Michigan,
2, Hays Innovations
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