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Patricia and John Rosenwald Laboratory of Neurobiology and Genetics
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Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease.
Neuron Jun, 2010 | Pubmed ID: 20547128
Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2010 | Pubmed ID: 21098282
Fibrinogen and altered hemostasis in Alzheimer's disease.
Journal of Alzheimer's disease : JAD , 2012 | Pubmed ID: 22869464
A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice.
The Journal of experimental medicine Jun, 2014 | Pubmed ID: 24821909
Biochemical and structural analysis of the interaction between β-amyloid and fibrinogen.
Blood 08, 2016 | Pubmed ID: 27389717
Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease.
Current opinion in hematology Sep, 2017 | Pubmed ID: 28661939
Aminopyrimidine Class Aggregation Inhibitor Effectively Blocks Aβ-Fibrinogen Interaction and Aβ-Induced Contact System Activation.
Biochemistry 02, 2018 | Pubmed ID: 29394041
Rockefeller University
Pradeep K. Singh*,1,
Hanna E. Berk-Rauch*,1,
Nadine Soplop2,
Kunihiro Uryu2,
Sidney Strickland1,
Hyung Jin Ahn1
1Patricia and John Rosenwald Laboratory of Neurobiology and Genetics, Rockefeller University,
2Electron Microscopy Resource Center, Rockefeller University
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