Jonathan P. Schneck

ImmunoMap: A Bioinformatics Tool for T-cell Repertoire Analysis.

Differential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62.

Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors.

Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients.

Lack of coreceptor allows survival of chronically stimulated double-negative alpha/beta T cells: implications for autoimmunity.

Development and use of multimeric major histocompatibility complex molecules.

T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.

Probing T cell membrane organization using dimeric MHC-Ig complexes.

Peptide-beta2-microglobulin-MHC fusion molecules bind antigen-specific T cells and can be used for multivalent MHC-Ig complexes.

Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells.

B220+ double-negative T cells suppress polyclonal T cell activation by a Fas-independent mechanism that involves inhibition of IL-2 production.

HLA-Ig-based artificial antigen-presenting cells: setting the terms of engagement.

Quality and quantity: new strategies to improve immunotherapy of cancer.

Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck.

Technological advances in adoptive immunotherapy.

Artificial antigen-presenting cells: artificial solutions for real diseases.

Antigen/MHC class II/Ig dimers for study of uveitogenic T cells: IRBP p161-180 presented by both IA and IE molecules.

Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis.

Gld mutation of Fas ligand increases the frequency and up-regulates cell survival genes in CD25+CD4+ TR cells.

Detection of antigen-specific T cells on p/MHC microarrays.

A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells.

Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically.

Killer artificial antigen-presenting cells: a novel strategy to delete specific T cells.

In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC).

Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers.

Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.

Ex vivo induction and expansion of natural killer T cells by CD1d1-Ig coated artificial antigen presenting cells.

Development of an artificial-antigen-presenting-cell-based assay for the detection of low-frequency virus-specific CD8(+) T cells in whole blood, with application for measles virus.

Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking.

In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.

Overview of a HLA-Ig based "Lego-like system" for T cell monitoring, modulation and expansion.

Dynamic regulation of functionally distinct virus-specific T cells.

Killer artificial antigen-presenting cells: the synthetic embodiment of a 'guided missile'.

High-throughput lectin microarray-based analysis of live cell surface glycosylation.

Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development.

Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors.

Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen.

Molecular identification of GD3 as a suppressor of the innate immune response in ovarian cancer.

T-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple HLA-I and -II binding motifs.

Nanoscale artificial antigen presenting cells for T cell immunotherapy.

Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells.

Sprouty-2 regulates HIV-specific T cell polyfunctionality.

Magnetic field-induced T cell receptor clustering by nanoparticles enhances T cell activation and stimulates antitumor activity.

Linking form to function: Biophysical aspects of artificial antigen presenting cell design.

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size.

Dual Targeting Nanoparticle Stimulates the Immune System To Inhibit Tumor Growth.

Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation.

Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.

Engineering Platforms for T Cell Modulation.

Efficient magnetic enrichment of antigen-specific T cells by engineering particle properties.