composition-distribution-analysis-bioaerosols-under-different

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions

Variable microorganisms in particulate matter (PM) under different environmental conditions may have significant impacts on human health. In this study, ...

Academy of Military Medical Sciences

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Author Correction: Avian Influenza H5N6 Viruses Exhibit Differing Pathogenicities and Transmissibilities in Mammals.

This study was performed to develop a murine aerosol infection model of brucellosis to investigate the pathogenicity and immune reactions induced by aerosolized Brucella and to identify key proteins associated with Brucella infection in lung tissue.

Immune response and differentially expressed proteins in the lung tissue of BALB/c mice challenged by aerosolized Brucella melitensis 5.

Particulate matter (PM), a major air pollutant in Beijing in recent years, poses a formidable public health threat. Even through many studies have documented the chemical and biological characteristics of PM, less is known about these characteristics on hazardous haze days (Air Quality Index, AQI 301-500) and the difference with sunny or unhealthy haze day (AQI 151-200) characteristics. Herein, studies were performed during a red alert air pollution event (continuous hazardous haze days) and the first few days following the event (sunny days first and then unhealthy haze days) in Beijing from December 19 to 25, 2016. A laser particle counter and an ANDERSEM-6 sampler were used to study the concentration and size distributions dynamics of the PM and the culturable airborne bacteria and fungi, respectively. PM was sampled by a high-volume air sampler and the chemical compositions, bacterial and fungal community structures, and endotoxin levels were analyzed. The results showed that the PM concentrations on the hazardous haze days and unhealthy haze days were 10.7 and 8.0 times higher, respectively, than those on the sunny days. The chemical composition of PM was highly correlated with the AQI. The concentration and percentage of water-soluble inorganic ions (WSII), which dominated the PM constituents, as well as the levels of endotoxin were higher on hazardous haze days than on unhealthy haze days and sunny days. Interestingly, the abundances of bacteria and fungi demonstrated the following order: unhealthy haze days> sunny days> hazardous haze days. Most culturable bacteria and fungi were distributed in particles with aerodynamic diameters of 2.1-4.7 μm. Redundancy analysis found total organic carbon explained 30.0% and 27.1% of total variations in bacterial composition and fungal composition at the genera level, respectively. Our results facilitate a better understanding of the biological and chemical composition dynamics of PM in Beijing.

Zhongyi Wang

Academy of Military Medical Sciences

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions