Graduate College of Biomedical Sciences
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Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer.
Nature genetics Jul, 2002 | Pubmed ID: 12053177
Long time dynamic simulations: exploring the folding pathways of an Alzheimer's amyloid Abeta-peptide.
Accounts of chemical research Jun, 2002 | Pubmed ID: 12069633
Results for a custom acetabular component for acetabular deficiency.
The Journal of arthroplasty Aug, 2002 | Pubmed ID: 12168183
Heterogeneous expression of transient outward currents in smooth muscle cells of the mouse small intestine.
The Journal of physiology Oct, 2002 | Pubmed ID: 12356877
Repression of IRF-4 target genes in human T cell leukemia virus-1 infection.
Oncogene Oct, 2002 | Pubmed ID: 12360402
Nuclear localization of cyclin B1 regulates DNA damage-induced apoptosis.
Blood Mar, 2003 | Pubmed ID: 12424202
Chronic flexibility gains: effect of isometric contraction duration during proprioceptive neuromuscular facilitation stretching techniques.
Research quarterly for exercise and sport Mar, 2003 | Pubmed ID: 12659475
Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis.
Journal of molecular medicine (Berlin, Germany) Sep, 2003 | Pubmed ID: 12898041
The role of protein elongation factor eEF1A2 in ovarian cancer.
Reproductive biology and endocrinology : RB&E Oct, 2003 | Pubmed ID: 14588074
Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor.
Journal of medicinal chemistry Jan, 2004 | Pubmed ID: 14736255
Independent cellular processes for hippocampal memory consolidation and reconsolidation.
Science (New York, N.Y.) May, 2004 | Pubmed ID: 15073322
Gene therapy in flap survival.
Microsurgery , 2004 | Pubmed ID: 15160373
The effect of preapplication of corticosteroids on skin irritation and performance of the GlucoWatch G2 Biographer.
Diabetes technology & therapeutics Jun, 2004 | Pubmed ID: 15198839
Does exaggerated morphology preclude plasticity to cuckoldry in the midshipman fish ( Porichthys notatus)?
Die Naturwissenschaften Jul, 2004 | Pubmed ID: 15257389
Factors predictive of tumor-positive nonsentinel lymph nodes after tumor-positive sentinel lymph node dissection for melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Sep, 2004 | Pubmed ID: 15365064
Contemporary surgical treatment of advanced-stage melanoma.
Archives of surgery (Chicago, Ill. : 1960) Sep, 2004 | Pubmed ID: 15381613
Thoracoabdominal aneurysm repair: anesthetic management.
International anesthesiology clinics , 2005 | Pubmed ID: 15632516
Quantitative analysis of melanoma-induced cytokine-mediated immunosuppression in melanoma sentinel nodes.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2005 | Pubmed ID: 15671534
p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription.
FEBS letters Feb, 2005 | Pubmed ID: 15710382
p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription.
Biochemical and biophysical research communications Apr, 2005 | Pubmed ID: 15737644
Differential effects of 11-ketotestosterone on dimorphic traits in a teleost with alternative male reproductive morphs.
Hormones and behavior May, 2005 | Pubmed ID: 15811353
Conditioned suppression and freezing as measures of aversive Pavlovian conditioning: effects of discrete amygdala lesions and overtraining.
Behavioural brain research Apr, 2005 | Pubmed ID: 15817185
Images in emergency medicine. Ectopic pregnancy.
Annals of emergency medicine Jun, 2005 | Pubmed ID: 15940106
Synthesis of the azaphilones using copper-mediated enantioselective oxidative dearomatization.
Journal of the American Chemical Society Jul, 2005 | Pubmed ID: 15984841
Catalytic ester-amide exchange using group (IV) metal alkoxide-activator complexes.
Journal of the American Chemical Society Jul, 2005 | Pubmed ID: 16011366
Vascularized bone grafting from the base of the second metacarpal for persistent distal radius nonunion: a case report.
Journal of orthopaedic trauma Aug, 2005 | Pubmed ID: 16056082
Anterior ischemic optic neuropathy complicating cranial vault reconstruction for sagittal synostosis in a child.
The Journal of craniofacial surgery Jul, 2005 | Pubmed ID: 16077298
Subglottic stenosis in short-statured children: a case for further investigation of airway symptoms in patients with skeletal dysplasias.
International journal of pediatric otorhinolaryngology Jan, 2006 | Pubmed ID: 16105694
Combined open septorhinoplasty and functional endoscopic sinus surgery.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Sep, 2005 | Pubmed ID: 16143196
Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior.
Neuron Sep, 2005 | Pubmed ID: 16157275
Melanoma recurrence patterns after negative sentinel lymphadenectomy.
Archives of surgery (Chicago, Ill. : 1960) Sep, 2005 | Pubmed ID: 16172295
Aminoethylation in model peptides reveals conditions for maximizing thiol specificity.
Archives of biochemistry and biophysics Nov, 2005 | Pubmed ID: 16229814
Discrepancies between roughness measurements obtained with phase-shifting and white-light interferometry.
Applied optics Oct, 2005 | Pubmed ID: 16231799
Antifibrogenic effects of liposome-encapsulated IFN-alpha2b cream on skin wounds in a fibrotic rabbit ear model.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research Oct, 2005 | Pubmed ID: 16241861
The earliest record of human activity in northern Europe.
Nature Dec, 2005 | Pubmed ID: 16355223
Application of gas microstrip detectors for X-ray absorption spectroscopy in common process gases.
Analytical chemistry Dec, 2003 | Pubmed ID: 16465709
Removed: Images in emergency medicine.
Annals of emergency medicine Jun, 2005 | Pubmed ID: 16482658
The epithelial-mesenchymal transition: new insights in signaling, development, and disease.
The Journal of cell biology Mar, 2006 | Pubmed ID: 16567498
Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2006 | Pubmed ID: 16738229
Extending the reach of the heterodigital arterialized flap by cross-finger transfer.
Plastic and reconstructive surgery Jun, 2006 | Pubmed ID: 16772937
Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer.
Breast cancer research and treatment Mar, 2007 | Pubmed ID: 16897428
Tumour-induced immune modulation of sentinel lymph nodes.
Nature reviews. Immunology Sep, 2006 | Pubmed ID: 16932751
Reconsolidation and extinction of conditioned fear: inhibition and potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2006 | Pubmed ID: 17005868
Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation.
The Journal of biological chemistry Jan, 2007 | Pubmed ID: 17088255
Disrupting reconsolidation of conditioned withdrawal memories in the basolateral amygdala reduces suppression of heroin seeking in rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2006 | Pubmed ID: 17151272
Effect of ring substitution position on the structural conformation of mercaptobenzoic acid self-assembled monolayers on Au(111).
Langmuir : the ACS journal of surfaces and colloids Dec, 2006 | Pubmed ID: 17154594
Mycobacterium marinum as a cause of chronic granulomatous tenosynovitis in the hand.
The Journal of infection Jun, 2007 | Pubmed ID: 17207859
Cyclin B1/Cdk1 binds and phosphorylates Filamin A and regulates its ability to cross-link actin.
FEBS letters Apr, 2007 | Pubmed ID: 17408621
Experimental observation of quantum confinement in the conduction band of CdSe quantum dots.
Physical review letters Apr, 2007 | Pubmed ID: 17501301
Molecular characterization of inflammatory genes in sentinel and nonsentinel nodes in melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2007 | Pubmed ID: 17545514
CCAAT/Enhancer binding protein beta abrogates retinoic acid-induced osteoblast differentiation via repression of Runx2 transcription.
Molecular endocrinology (Baltimore, Md.) Sep, 2007 | Pubmed ID: 17579210
A case report of seizure induced by bupropion nasal insufflation.
Primary care companion to the Journal of clinical psychiatry , 2007 | Pubmed ID: 17599174
The impact of nosocomially-acquired resistant Pseudomonas aeruginosa infection in a burn unit.
The Journal of trauma Jul, 2007 | Pubmed ID: 17622885
Factors affecting the prognosis of pyogenic flexor tenosynovitis.
The Journal of bone and joint surgery. American volume Aug, 2007 | Pubmed ID: 17671013
Structural development of mercaptophenol self-assembled monolayers and the overlying mineral phase during templated CaCO3 crystallization from a transient amorphous film.
Journal of the American Chemical Society Aug, 2007 | Pubmed ID: 17672454
Pneumatosis intestinalis in adults: management, surgical indications, and risk factors for mortality.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Oct, 2007 | Pubmed ID: 17687617
Geldanamycin anisimycins activate Rho and stimulate Rho- and ROCK-dependent actin stress fiber formation.
Molecular cancer research : MCR Sep, 2007 | Pubmed ID: 17855662
Enhancing the tuning range of a single resonant band long period grating while maintaining the resonant peak depth by using an optimized high index indium tin oxide overlay.
Applied optics Oct, 2007 | Pubmed ID: 17906728
Mutational analysis of the FXNPXY motif within LDL receptor-related protein 1 (LRP1) reveals the functional importance of the tyrosine residues in cell growth regulation and signal transduction.
The Biochemical journal Jan, 2008 | Pubmed ID: 17908054
Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct.
Journal of neuroscience research Apr, 2008 | Pubmed ID: 17972320
Operational trials of remote mosquito trap systems for Japanese encephalitis virus surveillance in the Torres Strait, Australia.
Vector borne and zoonotic diseases (Larchmont, N.Y.) , 2007 | Pubmed ID: 18021024
Diagnostic dilemmas in unusual presentations of gout.
Australian family physician Nov, 2007 | Pubmed ID: 18043781
Monocyte-derived IL-10 expression predicts prognosis of stage IV melanoma patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) Nov-Dec, 2007 | Pubmed ID: 18049335
Perfusion abnormalities in subchondral bone associated with marrow edema, osteoarthritis, and avascular necrosis.
Annals of the New York Academy of Sciences Nov, 2007 | Pubmed ID: 18056039
Flap resurfacing of postinfection soft-tissue defects of the hand.
Plastic and reconstructive surgery Dec, 2007 | Pubmed ID: 18090756
The prognostic significance of elongation factor eEF1A2 in ovarian cancer.
Gynecologic oncology Mar, 2008 | Pubmed ID: 18164751
Reconsolidation of appetitive memories for both natural and drug reinforcement is dependent on {beta}-adrenergic receptors.
Learning & memory (Cold Spring Harbor, N.Y.) Feb, 2008 | Pubmed ID: 18235109
Hylan versus corticosteroid versus placebo for treatment of basal joint arthritis: a prospective, randomized, double-blinded clinical trial.
The Journal of hand surgery Jan, 2008 | Pubmed ID: 18261664
The role of computed tomography of the chest in the staging of early squamous cell carcinoma of the tongue.
The British journal of oral & maxillofacial surgery Jul, 2008 | Pubmed ID: 18299162
The spiral flap for fingertip resurfacing: short-term and long-term results.
The Journal of hand surgery Mar, 2008 | Pubmed ID: 18343289
Appetitive memory reconsolidation depends upon NMDA receptor-mediated neurotransmission.
Neurobiology of learning and memory Jul, 2008 | Pubmed ID: 18372198
Prioritizing hits from phenotypic high-content screens.
Current opinion in drug discovery & development May, 2008 | Pubmed ID: 18428087
Free digital artery flap: an ideal flap for large finger defects in situations where local flaps are precluded.
Annals of plastic surgery Mar, 2008 | Pubmed ID: 18443505
Eukaryotic elongation factor 1A2 cooperates with phosphatidylinositol-4 kinase III beta to stimulate production of filopodia through increased phosphatidylinositol-4,5 bisphosphate generation.
Molecular and cellular biology Jul, 2008 | Pubmed ID: 18474610
Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation.
Learning & memory (Cold Spring Harbor, N.Y.) Jun, 2008 | Pubmed ID: 18509112
Near-edge X-ray absorption fine structure spectroscopy of diamondoid thiol monolayers on gold.
Journal of the American Chemical Society Aug, 2008 | Pubmed ID: 18642809
The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas.
International journal of cancer. Journal international du cancer Oct, 2008 | Pubmed ID: 18661515
Reactivation-dependent amnesia in Pavlovian approach and instrumental transfer.
Learning & memory (Cold Spring Harbor, N.Y.) Aug, 2008 | Pubmed ID: 18685151
Simultaneous infected pseudoaneurysm and suppurative tenosynovitis resulting from radial artery cannulation.
Surgical infections Aug, 2008 | Pubmed ID: 18687028
Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2008 | Pubmed ID: 18701685
Medicosocial problems engendered with the discovery of the Bell-Magendie Law.
Neurosurgery Jul, 2008 | Pubmed ID: 18728581
Resurfacing hemipulp losses of the thumb: the cross finger flap revisited: indications, technical refinements, outcomes, and long-term neurosensory recovery.
Annals of plastic surgery Oct, 2008 | Pubmed ID: 18812707
Memory reconsolidation mediates the strengthening of memories by additional learning.
Nature neuroscience Nov, 2008 | Pubmed ID: 18849987
Real-time PCR vs standard culture detection of group A beta-hemolytic streptococci at various anatomic sites in tonsillectomy patients.
Archives of otolaryngology--head & neck surgery Nov, 2008 | Pubmed ID: 19015447
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
American journal of physiology. Gastrointestinal and liver physiology Feb, 2009 | Pubmed ID: 19074643
A tuberculous midpalmar abscess of the hand due to reactivation of previous pulmonary tuberculosis.
Annals of the Academy of Medicine, Singapore Nov, 2008 | Pubmed ID: 19082210
Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor.
Molecular cancer therapeutics Jan, 2009 | Pubmed ID: 19139124
D-cycloserine potentiates the reconsolidation of cocaine-associated memories.
Learning & memory (Cold Spring Harbor, N.Y.) Jan, 2009 | Pubmed ID: 19144966
Determination of the exciton binding energy in CdSe quantum dots.
ACS nano Feb, 2009 | Pubmed ID: 19236067
Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging.
The Orthopedic clinics of North America Apr, 2009 | Pubmed ID: 19358910
Evidence for ligand-induced paramagnetism in CdSe quantum dots.
Journal of the American Chemical Society May, 2009 | Pubmed ID: 19415891
Mindfulness and emotion regulation difficulties in generalized anxiety disorder: preliminary evidence for independent and overlapping contributions.
Behavior therapy Jun, 2009 | Pubmed ID: 19433145
A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2009 | Pubmed ID: 19458050
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
The Journal of biological chemistry Jul, 2009 | Pubmed ID: 19465477
Reciprocal transmissions and asymmetric modal distributions in waveguide-coupled spiral-shaped microdisk resonators.
Optics express Oct, 2007 | Pubmed ID: 19550746
Biological factors, tumor growth kinetics, and survival after metastasectomy for pulmonary melanoma.
Annals of surgical oncology Oct, 2009 | Pubmed ID: 19603235
Identification of CITED2 as a negative regulator of fracture healing.
Biochemical and biophysical research communications Oct, 2009 | Pubmed ID: 19607804
Reconsolidation: maintaining memory relevance.
Trends in neurosciences Aug, 2009 | Pubmed ID: 19640595
Long-term follow-up of basal joint resection arthroplasty of the thumb with transfer of the abductor pollicis brevis origin to the flexor carpi radialis tendon.
The Journal of hand surgery Jul-Aug, 2009 | Pubmed ID: 19643289
Distress and avoidance in generalized anxiety disorder: exploring the relationships with intolerance of uncertainty and worry.
Cognitive behaviour therapy Jun, 2010 | Pubmed ID: 19714542
AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer.
Molecular cancer therapeutics Sep, 2009 | Pubmed ID: 19723882
An onco-informatics database for anticancer drug interactions with complementary and alternative medicines used in cancer treatment and supportive care: an overview of the OncoRx project.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Jul, 2010 | Pubmed ID: 19756775
Prosthetic valve endocarditis: clinicopathological correlates in 122 surgical specimens from 116 patients (1985-2004).
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Jan-Feb, 2011 | Pubmed ID: 19926308
Unanticipated C=C bonds in covalent monolayers on silicon revealed by NEXAFS.
Langmuir : the ACS journal of surfaces and colloids Feb, 2010 | Pubmed ID: 19938807
Sex differences in the uptake and disposition of perfluorooctanoic acid in fathead minnows after oral dosing.
Environmental science & technology Jan, 2010 | Pubmed ID: 19961202
Serotonin syndrome in a chronic-pain patient receiving concurrent methadone, ciprofloxacin, and venlafaxine.
Psychosomatics Nov-Dec, 2009 | Pubmed ID: 19996237
A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models.
PloS one , 2010 | Pubmed ID: 20140208
Matrix metalloproteinase-3 in articular cartilage is upregulated by joint immobilization and suppressed by passive joint motion.
Matrix biology : journal of the International Society for Matrix Biology Jun, 2010 | Pubmed ID: 20153826
Modified poly-L-lactic acid injection technique: safety and efficacy of "cross-fanning" in non-HIV-related facial atrophy.
Annals of plastic surgery Apr, 2010 | Pubmed ID: 20224335
An unusual case of turban tumor syndrome treated with total scalp excision and advancement flap and skin graft reconstruction.
Annals of plastic surgery Jul, 2010 | Pubmed ID: 20548229
Ultrafast optical switching based on nonlinear polarization rotation in silicon waveguides.
Optics express May, 2010 | Pubmed ID: 20589012
Can we faithfully recall what we remembered?
Discovery medicine Jun, 2004 | Pubmed ID: 20704983
The basolateral amygdala and nucleus accumbens core mediate dissociable aspects of drug memory reconsolidation.
Learning & memory (Cold Spring Harbor, N.Y.) Sep, 2010 | Pubmed ID: 20802017
Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Oct, 2010 | Pubmed ID: 20839322
Hazards of steroid injection: Suppurative extensor tendon rupture.
Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India Jan, 2010 | Pubmed ID: 20924461
Rice bodies, millet seeds, and melon seeds in tuberculous tenosynovitis of the hand and wrist.
Annals of plastic surgery Jun, 2011 | Pubmed ID: 20948407
Emergency physician referrals to the pediatric crisis clinic: reasons for referral, diagnosis and disposition.
Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Académie canadienne de psychiatrie de l'enfant et de l'adolescent Nov, 2010 | Pubmed ID: 21037921
The good oncogene: When bad genes identify good outcome in cancer.
Medical hypotheses Feb, 2011 | Pubmed ID: 21050670
Robust patterns in the stochastic organization of filopodia.
BMC cell biology , 2010 | Pubmed ID: 21083909
Memory reconsolidation mediates the updating of hippocampal memory content.
Frontiers in behavioral neuroscience , 2010 | Pubmed ID: 21120142
Polymeric cross-linked surface treatments for controlling block copolymer orientation in thin films.
Langmuir : the ACS journal of surfaces and colloids Mar, 2011 | Pubmed ID: 21214210
Identification of Schistosoma mansoni microRNAs.
BMC genomics , 2011 | Pubmed ID: 21247453
A quantitative, facile, and high-throughput image-based cell migration method is a robust alternative to the scratch assay.
Journal of biomolecular screening Feb, 2011 | Pubmed ID: 21297103
The role of values-consistent behavior in generalized anxiety disorder.
Depression and anxiety May, 2011 | Pubmed ID: 21308890
Molecular analysis of melanoma-induced sentinel lymph node immune dysfunction.
Cancer immunology, immunotherapy : CII May, 2011 | Pubmed ID: 21327637
Moderators of chronic disease self-management programs: who benefits?
Chronic illness Jun, 2011 | Pubmed ID: 21357642
Autogenic heterotopic vascularized proximal interphalangeal joint transplantation in children.
Microsurgery Mar, 2011 | Pubmed ID: 21374712
BMP-12 treatment of adult mesenchymal stem cells in vitro augments tendon-like tissue formation and defect repair in vivo.
PloS one , 2011 | Pubmed ID: 21412429
Open innovation for phenotypic drug discovery: The PD2 assay panel.
Journal of biomolecular screening Jul, 2011 | Pubmed ID: 21521801
The development of a brief acceptance and mindfulness-based program aimed at reducing sexual revictimization among college women with a history of childhood sexual abuse.
Journal of clinical psychology Sep, 2011 | Pubmed ID: 21544818
The lipid kinase PI4KIIIβ and the eEF1A2 oncogene co-operate to disrupt three-dimensional in vitro acinar morphogenesis.
Experimental cell research Oct, 2011 | Pubmed ID: 21851817
Laboratory diagnosis of factitious disorder: a systematic review of tools useful in the diagnosis of Munchausen's syndrome.
The New Zealand medical journal Sep, 2011 | Pubmed ID: 21963927
Processes of care and outcomes for community-acquired pneumonia.
The American journal of medicine Dec, 2011 | Pubmed ID: 22000624
Behavioural memory reconsolidation of food and fear memories.
Nature communications , 2011 | Pubmed ID: 22009036
Essential role for phosphatidylinositol 4,5-bisphosphate in the expression, regulation, and gating of the slow afterhyperpolarization current in the cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2011 | Pubmed ID: 22171034
Slow-light dispersion in periodically patterned silicon microring resonators.
Optics letters Jan, 2012 | Pubmed ID: 22212790
Influence of Mesoporosity on Lithium-Ion Storage Capacity and Rate Performance of Nanostructured TiO(2)(B).
Langmuir : the ACS journal of surfaces and colloids Feb, 2012 | Pubmed ID: 22225480
Homoepitaxial Growth of Single Crystal Diamond Membranes for Quantum Information Processing.
Advanced materials (Deerfield Beach, Fla.) Jan, 2012 | Pubmed ID: 22290655