S'identifier

Aubryanna Hettinghouse

Department of Orthopaedic Surgery

New York University Medical Center

BIOGRAPHY

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PUBLICATIONS

Chondro-protective effects of low intensity pulsed ultrasound.

Osteoarthritis and cartilage 11, 2016 | Pubmed ID: 27364595

The role of progranulin in arthritis.

Annals of the New York Academy of Sciences 11, 2016 | Pubmed ID: 27505256

Multifunctional molecule ERp57: From cancer to neurodegenerative diseases.

Pharmacology & therapeutics 01, 2018 | Pubmed ID: 28723413

Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes.

Genes & diseases Sep, 2017 | Pubmed ID: 28944282

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models.

Arthritis research & therapy Dec, 2017 | Pubmed ID: 29258611

Molecular regulations and therapeutic targets of Gaucher disease.

Cytokine & growth factor reviews 06, 2018 | Pubmed ID: 29699937

Role of ADAMTS-12 in Protecting Against Inflammatory Arthritis in Mice By Interacting With and Inactivating Proinflammatory Connective Tissue Growth Factor.

Arthritis & rheumatology (Hoboken, N.J.) 11, 2018 | Pubmed ID: 29750395

Targeting tumor necrosis factor receptors in ankylosing spondylitis.

Annals of the New York Academy of Sciences Apr, 2019 | Pubmed ID: 30008173

Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease.

Journal of molecular medicine (Berlin, Germany) Dec, 2018 | Pubmed ID: 30341570

Brain-penetrant heat shock protein amplifier arimoclomol enhances GCase activity in in vitro Gaucher disease models.

EBioMedicine 12, 2018 | Pubmed ID: 30522930

Clinical Application of Teriparatide in Fracture Prevention: A Systematic Review.

JBJS reviews Jan, 2019 | Pubmed ID: 30694878

Progranulin: A conductor of receptors orchestra, a chaperone of lysosomal enzymes and a therapeutic target for multiple diseases.

Cytokine & growth factor reviews 02, 2019 | Pubmed ID: 30733059

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis.

Annals of the rheumatic diseases Jul, 2019 | Pubmed ID: 31302596

Progranulin promotes diabetic fracture healing in mice with type 1 diabetes.

Annals of the New York Academy of Sciences Aug, 2019 | Pubmed ID: 31423598

INSTITUTIONS

New York University Medical Center

JOVE ARTICLES

A Semi-Quantitative Drug Affinity Responsive Target Stability (DARTS) assay for studying Rapamycin/mTOR interaction

Chen Zhang^*,1,

Min Cui^*,1,

Yazhou Cui¹,

Aubryanna Hettinghouse¹,

Chuan-ju Liu^1,2

¹Department of Orthopaedic Surgery, New York University Medical Center,

²Department of Cell Biology, New York University School of Medicine

Biochemistry

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Aubryanna Hettinghouse

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Orthopaedic Surgery

New York University Medical Center

A Semi-Quantitative Drug Affinity Responsive Target Stability (DARTS) assay for studying Rapamycin/mTOR interaction

Department of Orthopaedic Surgery