S'identifier

Jiajun Yap

The Laboratory of Cancer Signaling,
Division of Cellular and Molecular Research,
The Laboratory of Cancer Signaling, Division of Cellular and Molecular Research

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PUBLICATIONS

The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants.

Oncogene 10, 2018 | Pubmed ID: 29930381

The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF.

The Journal of biological chemistry 09, 2018 | Pubmed ID: 30030377

Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis.

Science signaling Oct, 2018 | Pubmed ID: 30377225

INSTITUTIONS

National Cancer Centre Singapore

JOVE ARTICLES

Jiajun Yap¹,

Jimin Yuan¹,

Zi Heng Tee¹,

Xuchao Huang¹,

Wan Hwa Ng¹,

Jiancheng Hu^1,2

¹The Laboratory of Cancer Signaling, Division of Cellular and Molecular Research, National Cancer Centre Singapore,

²The Cancer and Stem Cell Program, Duke-NUS Medical School

Cancer Research

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