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McConnell Brain Imaging Centre,
Montreal Neurological Institute,
Department of Neurology and Neurosurgery,
McConnell Brain Imaging Centre, Montreal Neurological Institute
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Where in-vivo imaging meets cytoarchitectonics: the relationship between cortical thickness and neuronal density measured with high-resolution [18F]flumazenil-PET.
NeuroImage Jun, 2011 | Pubmed ID: 21073964
t-Bu2SiF-derivatized D2-receptor ligands: the first SiFA-containing small molecule radiotracers for target-specific PET-imaging.
Molecules (Basel, Switzerland) Sep, 2011 | Pubmed ID: 21892125
Oxalic acid supported Si-18F-radiofluorination: one-step radiosynthesis of N-succinimidyl 3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for protein labeling.
Bioconjugate chemistry Jan, 2012 | Pubmed ID: 22148255
Synthesis of [(18)F]SiFB: a prosthetic group for direct protein radiolabeling for application in positron emission tomography.
Nature protocols Nov, 2012 | Pubmed ID: 23037310
GABAA receptors predict aversion-related brain responses: an fMRI-PET investigation in healthy humans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jul, 2013 | Pubmed ID: 23389691
Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry.
EJNMMI research Oct, 2013 | Pubmed ID: 24103360
Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography.
International journal of molecular imaging , 2013 | Pubmed ID: 24324884
¹⁸F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.
BioMed research international , 2014 | Pubmed ID: 25157357
Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.
ACS chemical neuroscience Feb, 2015 | Pubmed ID: 25350780
In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.
Brain structure & function Apr, 2016 | Pubmed ID: 25596865
In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Jul, 2015 | Pubmed ID: 25977461
Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1.
Cerebrovascular diseases (Basel, Switzerland) , 2016 | Pubmed ID: 26752046
Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile.
Bioorganic & medicinal chemistry 10, 2016 | Pubmed ID: 27567078
Development of "[C]kits" for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine Mar, 2017 | Pubmed ID: 28038410
A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human.
Journal of medicinal chemistry 08, 2017 | Pubmed ID: 28696690
Highly efficient solid phase supported radiosynthesis of [ C]PiB using tC18 cartridge as a "3-in-1" production entity.
Journal of labelled compounds & radiopharmaceuticals 12, 2017 | Pubmed ID: 28981146
Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities.
The Journal of neuroscience : the official journal of the Society for Neuroscience 12, 2017 | Pubmed ID: 29097597
[F]ODIBO: a prosthetic group for bioorthogonal radiolabeling of macromolecules via strain-promoted alkyne-azide cycloaddition.
Organic & biomolecular chemistry 01, 2018 | Pubmed ID: 29170778
Identification of [F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging.
Journal of medicinal chemistry 02, 2018 | Pubmed ID: 29257860
A simplified radiosynthesis of [ F]MK-6240 for tau PET imaging.
Journal of labelled compounds & radiopharmaceuticals 02, 2019 | Pubmed ID: 30426529
Effect of (Z)-isomer content on [C]ABP688 binding potential in humans.
European journal of nuclear medicine and molecular imaging May, 2019 | Pubmed ID: 30607444
Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging.
Pharmaceuticals (Basel, Switzerland) Jan, 2019 | Pubmed ID: 30609832
Radiosynthesis of the diastereomerically pure (E)-[ C]ABP688.
Journal of labelled compounds & radiopharmaceuticals Aug, 2019 | Pubmed ID: 31418468
McGill University
Thomas A. Singleton*,1,
Mehdi Boudjemeline*,1,
Robert Hopewell1,
Dean Jolly1,
Hussein Bdair1,
Alexey Kostikov1,2
1McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University,
2Department of Neurology and Neurosurgery, McGill University
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