Department of Motor Function Analysis,
Human Health Sciences,
Graduate School of Medicine,
Department of Motor Function Analysis, Human Health Sciences, Graduate School of Medicine
ITO Akira is a physical therapist. He obtained a Physical therapy license in 2003.
He obtained his PhD in Human Health Sciences at Kyoto University, Japan in 2015.
Since April 2016, he is an assistant professor at the Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University.
He worked as a physical therapist at a hospital and gained valuable experience treating patients with a variety of pathologies including osteoarthritis and central/peripheral nerve injuries. He also studied molecular and cellular biology, animal experimentation, and various analytical methods. From these experiences, he have gained sufficient knowledge in the fields of rehabilitation and cellular biology that formed the foundation for his current research focus in the field of Regenerative Rehabilitation. His long-term research interests involve the elucidation of the effects and underlying mechanisms of physical therapy for regenerative medicine. Ultimately, he is interested in clinically translating these findings into the development of more effective physical therapies.
Prostaglandin F(2alpha), cytokines and cyclic mechanical stretch augment matrix metalloproteinase-1 secretion from cultured human uterine cervical fibroblast cells.
Molecular human reproduction Jul, 2002 | Pubmed ID: 12087084
Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry.
The American journal of cardiology Apr, 2011 | Pubmed ID: 21296326
The first workshop towards the control of cestode zoonoses in Asia and Africa.
Parasites & vectors Jun, 2011 | Pubmed ID: 21693001
Antiplatelet therapy and long-term clinical outcome after sirolimus-eluting stent implantation: 5-year outcome of the j-Cypher registry.
Cardiovascular intervention and therapeutics Sep, 2012 | Pubmed ID: 22695921
Low-intensity pulsed ultrasound inhibits messenger RNA expression of matrix metalloproteinase-13 induced by interleukin-1β in chondrocytes in an intensity-dependent manner.
Ultrasound in medicine & biology Oct, 2012 | Pubmed ID: 22920551
Effects of exercise level on biomarkers in a rat knee model of osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jul, 2013 | Pubmed ID: 23483591
Optimum temperature for extracellular matrix production by articular chondrocytes.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group Mar, 2014 | Pubmed ID: 24499154
Immature articular cartilage and subchondral bone covered by menisci are potentially susceptive to mechanical load.
BMC musculoskeletal disorders Mar, 2014 | Pubmed ID: 24669849
Evaluation of reference genes for human chondrocytes cultured in several different thermal environments.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group May, 2014 | Pubmed ID: 24773042
Phylogenetic characterisation of Taenia tapeworms in spotted hyenas and reconsideration of the "Out of Africa" hypothesis of Taenia in humans.
International journal for parasitology Jul, 2014 | Pubmed ID: 24815426
Contributions of biarticular myogenic components to the limitation of the range of motion after immobilization of rat knee joint.
BMC musculoskeletal disorders Jul, 2014 | Pubmed ID: 25001065
Regional comparisons of porcine menisci.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Dec, 2014 | Pubmed ID: 25196310
Culture temperature affects redifferentiation and cartilaginous extracellular matrix formation in dedifferentiated human chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society May, 2015 | Pubmed ID: 25641400
Discordance in recovery between altered locomotion and muscle atrophy induced by simulated microgravity in rats.
Journal of motor behavior , 2015 | Pubmed ID: 25789843
Effects of the thermal environment on articular chondrocyte metabolism: a fundamental study to facilitate establishment of an effective thermotherapy for osteoarthritis.
Journal of the Japanese Physical Therapy Association = Rigaku ryoho , 2014 | Pubmed ID: 25792904
Intermittent application of hypergravity by centrifugation attenuates disruption of rat gait induced by 2 weeks of simulated microgravity.
Behavioural brain research , 2015 | Pubmed ID: 25819803
The present situation and towards the prevention and control of neurocysticercosis on the tropical island, Bali, Indonesia.
Parasites & vectors Mar, 2015 | Pubmed ID: 25881045
Alteration of cartilage surface collagen fibers differs locally after immobilization of knee joints in rats.
Journal of anatomy May, 2015 | Pubmed ID: 25939458
Culture temperature affects human chondrocyte messenger RNA expression in monolayer and pellet culture systems.
PloS one , 2015 | Pubmed ID: 26010859
The effects of short-term hypoxia on human mesenchymal stem cell proliferation, viability and p16(INK4A) mRNA expression: Investigation using a simple hypoxic culture system with a deoxidizing agent.
Journal of stem cells & regenerative medicine , 2015 | Pubmed ID: 26195892
Effect of microfabricated microgroove-surface devices on the morphology of mesenchymal stem cells.
Biomedical microdevices Dec, 2015 | Pubmed ID: 26573821
The Effect of Exercise on the Early Stages of Mesenchymal Stromal Cell-Induced Cartilage Repair in a Rat Osteochondral Defect Model.
PloS one , 2016 | Pubmed ID: 26968036
Remobilization causes site-specific cyst formation in immobilization-induced knee cartilage degeneration in an immobilized rat model.
Journal of anatomy 06, 2016 | Pubmed ID: 26989984
Simple Identification of Human Taenia Species by Multiplex Loop-Mediated Isothermal Amplification in Combination with Dot Enzyme-Linked Immunosorbent Assay.
The American journal of tropical medicine and hygiene 06, 2016 | Pubmed ID: 27044566
Swine cysticercosis in the Karangasem district of Bali, Indonesia: An evaluation of serological screening methods.
Acta tropica Nov, 2016 | Pubmed ID: 27480240
Effect of Low-Intensity Pulsed Ultrasound after Mesenchymal Stromal Cell Injection to Treat Osteochondral Defects: An In Vivo Study.
Ultrasound in medicine & biology 12, 2016 | Pubmed ID: 27600474
Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion.
The Journal of veterinary medical science Feb, 2017 | Pubmed ID: 27890868
Physiological exercise loading suppresses post-traumatic osteoarthritis progression via an increase in bone morphogenetic proteins expression in an experimental rat knee model.
Osteoarthritis and cartilage 06, 2017 | Pubmed ID: 27965139
The efficacy of a scaffold-free Bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model.
PloS one , 2017 | Pubmed ID: 28192527
Relationships Between Quantitative Pulse-Echo Ultrasound Parameters from the Superficial Zone of the Human Articular Cartilage and Changes in Surface Roughness, Collagen Content or Collagen Orientation Caused by Early Degeneration.
Ultrasound in medicine & biology 08, 2017 | Pubmed ID: 28499496
Pathohistological investigation of osteochondral tissue obtained during total knee arthroplasty after osteochondral autologous transfer: a case report.
BMC research notes Jun, 2017 | Pubmed ID: 28587673
Taenia solium, Taenia saginata, Taenia asiatica, their hybrids and other helminthic infections occurring in a neglected tropical diseases' highly endemic area in Lao PDR.
PLoS neglected tropical diseases 02, 2018 | Pubmed ID: 29420601
Ultrasound Parameters for Human Osteoarthritic Subchondral Bone ex Vivo: Comparison with Micro-Computed Tomography Parameters.
Ultrasound in medicine & biology 10, 2018 | Pubmed ID: 30064850
Three-dimensional motion analysis for comprehensive understanding of gait characteristics after sciatic nerve lesion in rodents.
Scientific reports 09, 2018 | Pubmed ID: 30206259
Identification of a previously unidentified endemic region for taeniasis in North Sumatra, Indonesia.
Acta tropica Jan, 2019 | Pubmed ID: 30321521
Towards a cysticercosis-free tropical resort island: A historical overview of taeniasis/cysticercosis in Bali.
Acta tropica Feb, 2019 | Pubmed ID: 30385216
Functional evaluation outcomes correlate with histomorphometric changes in the rat sciatic nerve crush injury model: A comparison between sciatic functional index and kinematic analysis.
PloS one , 2018 | Pubmed ID: 30540822
Periodic mild heat stimuli diminish extracellular matrix synthesis in pellet cultured human chondrocytes.
BMC research notes Jan, 2019 | Pubmed ID: 30642366
Magnetically triggered transgene expression in mammalian cells by localized cellular heating of magnetic nanoparticles.
Journal of bioscience and bioengineering Sep, 2019 | Pubmed ID: 30962099
Therapeutic effects of combined cell transplantation and locomotor training in rats with brain injury.
NPJ Regenerative medicine , 2019 | Pubmed ID: 31231547
Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles.
Acta tropica Oct, 2019 | Pubmed ID: 31295430
Three-dimensional motion analysis for evaluating motor function in rodents with peripheral nerve injury.
Neural regeneration research Dec, 2019 | Pubmed ID: 31397339
Lower-body positive pressure diminishes surface blood flow reactivity during treadmill walking.
BMC research notes Nov, 2019 | Pubmed ID: 31703730
Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field.
Archives of physical medicine and rehabilitation Feb, 2020 | Pubmed ID: 32035141
Regenerative Rehabilitation for Stroke Recovery by Inducing Synergistic Effects of Cell Therapy and Neurorehabilitation on Motor Function: A Narrative Review of Pre-Clinical Studies.
International journal of molecular sciences Apr, 2020 | Pubmed ID: 32365542
Ultrasound therapy with optimal intensity facilitates peripheral nerve regeneration in rats through suppression of pro-inflammatory and nerve growth inhibitor gene expression.
PloS one , 2020 | Pubmed ID: 32555658
Effects of in vivo cyclic compressive loading on the distribution of local Col2 and superficial lubricin in rat knee cartilage.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 03, 2021 | Pubmed ID: 32716572
Magnetic heating of nanoparticles as a scalable cryopreservation technology for human induced pluripotent stem cells.
Scientific reports 08, 2020 | Pubmed ID: 32788637
Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts.
Journal of reconstructive microsurgery May, 2021 | Pubmed ID: 32957155
Quantitative Parameters for the Degeneration in Cartilage and Subchondral Bone of Human Knee by 3-D Ultrasound Scanning System.
Ultrasound in medicine & biology 12, 2020 | Pubmed ID: 32980159
A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.
Scientific reports 11, 2020 | Pubmed ID: 33247195
Origin of the pork tapeworm Taenia solium in Bali and Papua, Indonesia.
Parasitology international Aug, 2021 | Pubmed ID: 33486126
Low-Intensity Pulsed Ultrasound Prompts Both Functional and Histologic Improvements While Upregulating the Brain-Derived Neurotrophic Factor Expression after Sciatic Crush Injury in Rats.
Ultrasound in medicine & biology Jun, 2021 | Pubmed ID: 33745752
Intramyocardial Transplantation of Human iPS Cell-Derived Cardiac Spheroids Improves Cardiac Function in Heart Failure Animals.
JACC. Basic to translational science Mar, 2021 | Pubmed ID: 33778211
Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.
Scientific reports Mar, 2021 | Pubmed ID: 33782495
Interfacial polarization of in vivo rat sciatic nerve with crush injury studied via broadband dielectric spectroscopy.
PloS one , 2021 | Pubmed ID: 34077459
Risk factors and prevalence of taeniasis among the Karen people of Tha Song Yang District, Tak Province, Thailand.
Parasite (Paris, France) , 2021 | Pubmed ID: 34142955
Intra-Articular Injections of Curcumin Monoglucuronide TBP1901 Suppresses Articular Cartilage Damage and Regulates Subchondral Bone Alteration in an Osteoarthritis Rat Model.
Cartilage 12, 2021 | Pubmed ID: 34474599
Contractile Activity of Myotubes Derived from Human Induced Pluripotent Stem Cells: A Model of Duchenne Muscular Dystrophy.
Cells 09, 2021 | Pubmed ID: 34685536
Investigating the Optimal Initiation Time of Ultrasound Therapy for Peripheral Nerve Regeneration after Axonotmesis in Rats.
Ultrasound in medicine & biology 02, 2022 | Pubmed ID: 34740495
Effect of a Rehabilitation Program After Mesenchymal Stromal Cell Transplantation for Advanced Osteonecrosis of the Femoral Head: A 10-Year Follow-Up Study.
Archives of rehabilitation research and clinical translation Mar, 2022 | Pubmed ID: 35282152
1Department of Development and Rehabilitation of Motor Function, Human Health Sciences, Graduate School of Medicine, Kyoto University,
2Department of Motor Function Analysis, Human Health Sciences, Graduate School of Medicine, Kyoto University,
3Department of Otolaryngology, The Ohio State University Wexner Medical Center