S'identifier

Mukul Girotra

Department of Oncology UNIL CHUV,
Ludwig Institute for Cancer Research Lausanne,
Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne

University of Lausanne

BIOGRAPHY

Dr. Mukul Girotra received his Masters in Biology from the Tata Institute of Fundamental Research, India and his PhD in Bioengineering from the École Polytechnique Fédérale de Lausanne, Switzerland. His doctoral work focused on metabolic regulation of hematopoietic stem cell (HSC) function, where he established the role of mitochondrial activity in determining HSC fate. As a scientist now at the Ludwig Institute for Cancer Research he studies mouse and human hematopoietic stem cell metabolism in the context of aging, hematological malignancies and cancer-immunotherapy. He collaborates with pharma and healthcare industry to find novel nutritional candidates to boost HSC function.

PUBLICATIONS

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.

Nature communications 09, 2017 | Pubmed ID: 28928446

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

Cell stem cell 03, 2019 | Pubmed ID: 30849366

INSTITUTIONS

University of Lausanne

Swiss Federal Institute of Technology Lausanne (EPFL)

JOVE ARTICLES

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry

Mukul Girotra^*,1,2,

Anne-Christine Thierry³,

Alexandre Harari^1,3,

George Coukos¹,

Olaia Naveiras^2,4,

Nicola Vannini^*,1

¹Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne, University of Lausanne,

²Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL),

³Center of Experimental Therapeutics, Department of Oncology, Centre Hospitalier Universitaire Vaudois,

⁴Hematology Service, Department of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV)

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Mukul Girotra

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Oncology UNIL CHUV,Ludwig Institute for Cancer Research Lausanne,Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne

University of Lausanne

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry

Department of Oncology UNIL CHUV,
Ludwig Institute for Cancer Research Lausanne,
Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne