Amanda L. Lewis

Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact.

Discovery and characterization of sialic acid O-acetylation in group B Streptococcus.

A human-specific gene in microglia.

The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters.

Group B streptococcal capsular sialic acids interact with siglecs (immunoglobulin-like lectins) on human leukocytes.

NeuA sialic acid O-acetylesterase activity modulates O-acetylation of capsular polysaccharide in group B Streptococcus.

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.

Group B streptococcal conjugate vaccines elicit functional antibodies independent of strain O-acetylation.

Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure.

O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence.

Genomic and metabolic profiling of nonulosonic acids in Vibrionaceae reveal biochemical phenotypes of allelic divergence in Vibrio vulnificus.

Expression of sialic acids and other nonulosonic acids in Leptospira.

Evolutionary inactivation of a sialidase in group B Streptococcus.

Human milk oligosaccharides inhibit growth of group B .

USPSTF 2020 Recommendations on Screening for Asymptomatic Bacterial Vaginosis in Pregnancy.

The structure and diversity of strain-level variation in vaginal bacteria.

Vaginal sialoglycan foraging by Gardnerella vaginalis: mucus barriers as a meal for unwelcome guests?

A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection.

Bladder Exposure to Activates Host Pathways Necessary for Recurrent UTI.