Robin F. Krimm

NT3 expressed in skin causes enhancement of SA1 sensory neurons that leads to postnatal enhancement of Merkel cells.

Neuron/target plasticity in the peripheral gustatory system.

Epithelial overexpression of BDNF and NT4 produces distinct gustatory axon morphologies that disrupt initial targeting.

Refinement of innervation accuracy following initial targeting of peripheral gustatory fibers.

Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number.

Mice lacking the p75 receptor fail to acquire a normal complement of taste buds and geniculate ganglion neurons by adulthood.

Factors that regulate embryonic gustatory development.

Exuberant neuronal convergence onto reduced taste bud targets with preservation of neural specificity in mice overexpressing neurotrophin in the tongue epithelium.

Epithelial-derived brain-derived neurotrophic factor is required for gustatory neuron targeting during a critical developmental period.

Fate mapping of mammalian embryonic taste bud progenitors.

BDNF is required for the survival of differentiated geniculate ganglion neurons.

Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferents.

Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system.

Neurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factor.

BDNF and NT4 play interchangeable roles in gustatory development.

Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulation.

The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development.

Postnatal reduction of BDNF regulates the developmental remodeling of taste bud innervation.

Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds.

Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds.

TrkB expression and dependence divides gustatory neurons into three subpopulations.