Lena Allweiss

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus.

Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection.

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism.

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection.

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.

Experimental in vitro and in vivo models for the study of human hepatitis B virus infection.

Serum HBV pgRNA as a clinical marker for cccDNA activity.

Immunofluorescent Staining for the Detection of the Hepatitis B Core Antigen in Frozen Liver Sections of Human Liver Chimeric Mice.

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.

The Role of cccDNA in HBV Maintenance.

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection.

Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.

T cell receptor grafting allows virological control of Hepatitis B virus infection.

Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection.

Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes.

In-vitro and in-vivo models for hepatitis B cure research.

Multiorgan and Renal Tropism of SARS-CoV-2.

A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenance.

Murine hepatocytes do not support persistence of Hepatitis D virus mono-infection in vivo.

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series.

Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo.