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Dept. Cell Chemical Biology
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BMP signaling in vascular diseases.
FEBS letters Jul, 2012 | Pubmed ID: 22710160
Antisense-oligonucleotide mediated exon skipping in activin-receptor-like kinase 2: inhibiting the receptor that is overactive in fibrodysplasia ossificans progressiva.
PloS one , 2013 | Pubmed ID: 23861958
Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva.
European journal of human genetics : EJHG Oct, 2015 | Pubmed ID: 25604857
SLUG is expressed in endothelial cells lacking primary cilia to promote cellular calcification.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2015 | Pubmed ID: 25633317
Osteochondromas in fibrodysplasia ossificans progressiva: a widespread trait with a streaking but overlooked appearance when arising at femoral bone end.
Rheumatology international Oct, 2015 | Pubmed ID: 26049728
Bone morphogenetic protein signaling in bone homeostasis.
Bone Nov, 2015 | Pubmed ID: 26051467
Bone morphogenetic protein 6 and oxidized low-density lipoprotein synergistically recruit osteogenic differentiation in endothelial cells.
Cardiovascular research Nov, 2015 | Pubmed ID: 26410368
In Brief: Endothelial-to-mesenchymal transition.
The Journal of pathology Feb, 2016 | Pubmed ID: 26446982
Signal Transduction: Gain of Activin Turns Muscle into Bone.
Current biology : CB Dec, 2015 | Pubmed ID: 26654374
Emerging regulators of BMP bioavailability.
Bone Dec, 2016 | Pubmed ID: 26825814
Towards a cure for Fibrodysplasia ossificans progressiva.
Annals of translational medicine Oct, 2016 | Pubmed ID: 27867996
Involvement of inflammation and its related microRNAs in hepatocellular carcinoma.
Oncotarget Mar, 2017 | Pubmed ID: 27888618
Endothelial-to-mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry.
Developmental dynamics : an official publication of the American Association of Anatomists 03, 2018 | Pubmed ID: 28891150
TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases.
International journal of molecular sciences Oct, 2017 | Pubmed ID: 29039786
The therapeutic potential of targeting the endothelial-to-mesenchymal transition.
Angiogenesis 02, 2019 | Pubmed ID: 30076548
Bone morphogenetic protein receptor signal transduction in human disease.
The Journal of pathology 01, 2019 | Pubmed ID: 30246251
Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2.
The Journal of pathology 03, 2019 | Pubmed ID: 30430573
Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve.
International journal of molecular sciences Jul, 2019 | Pubmed ID: 31269711
Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts.
Stem cell research 12, 2019 | Pubmed ID: 31733439
Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells.
JBMR plus Nov, 2019 | Pubmed ID: 31768489
Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Cancer cell 03, 2020 | Pubmed ID: 32142668
TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 32373613
Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors.
Bone Sep, 2020 | Pubmed ID: 32522605
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells.
Angiogenesis 11, 2020 | Pubmed ID: 32813135
Leiden University Medical Center
Jin Ma1,2,
Gerard van der Zon1,2,
Gonzalo Sanchez-Duffhues1,
Peter ten Dijke1,2
1Dept. Cell Chemical Biology, Leiden University Medical Center,
2Oncode Institute, Leiden University Medical Center
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