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Retroviral Replication Laboratory
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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
PLoS pathogens Oct, 2015 | Pubmed ID: 26431200
HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription.
Retrovirology Aug, 2016 | Pubmed ID: 27549239
SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells.
Scientific reports 02, 2017 | Pubmed ID: 28220857
Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis.
PLoS pathogens 06, 2018 | Pubmed ID: 29906285
Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins.
Microbial cell (Graz, Austria) Jul, 2018 | Pubmed ID: 30175108
Positive selection in dNTPase SAMHD1 throughout mammalian evolution.
Proceedings of the National Academy of Sciences of the United States of America 09, 2019 | Pubmed ID: 31451672
HIV-1 Gag recruits oligomeric Vpr via two binding sites in p6, but both mature p6 and Vpr are rapidly lost upon target cell entry.
Journal of virology Jun, 2021 | Pubmed ID: 34106747
The Francis Crick Institute
Paula Ordonez1,
Kate N. Bishop2,
Jonathan P. Stoye1,
Harriet Cordelia Theed Groom3
1Retrovirus-Host Interactions Laboratory, The Francis Crick Institute,
2Retroviral Replication Laboratory, The Francis Crick Institute,
3Sidney Sussex College, Department of Medicine, University of Cambridge
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