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Department of Neuroscience Care and Society,
Division of Neurogeriatrics,
Department of Neuroscience Care and Society, Division of Neurogeriatrics
Pavel F. Pavlov has not added Biography.
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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18757748
Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis.
Journal of cellular and molecular medicine Oct, 2009 | Pubmed ID: 19725915
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Neurochemistry international Nov, 2010 | Pubmed ID: 20705111
Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2011 | Pubmed ID: 20833873
Abnormal platelet amyloid-β protein precursor (AβPP) metabolism in Alzheimer's disease: identification and characterization of a new AβPP isoform as potential biomarker.
Journal of Alzheimer's disease : JAD , 2013 | Pubmed ID: 23388171
Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation.
Journal of neurochemistry Feb, 2016 | Pubmed ID: 26500157
Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.
Scientific reports 10, 2017 | Pubmed ID: 29079741
Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease.
Journal of cellular and molecular medicine 07, 2018 | Pubmed ID: 29704317
identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network.
FEBS open bio Nov, 2018 | Pubmed ID: 30410862
Metal Binding by GMP-1 and Its Pyrimido [1, 2]benzimidazole Analogs Confirms Protection Against Amyloid-β Associated Neurotoxicity.
Journal of Alzheimer's disease : JAD , 2020 | Pubmed ID: 31839606
Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance.
European journal of medicinal chemistry Jan, 2021 | Pubmed ID: 33139110
Karolinska Institutet
Lisha Wang1,
Liza Bergkvist1,
Rajnish Kumar1,2,
Bengt Winblad1,3,
Pavel F. Pavlov1
1Department of Neuroscience Care and Society, Division of Neurogeriatrics, Karolinska Institutet,
2Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (BHU),
3Theme Inflammation and Aging, Karolinska University Hospital
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