Department of Pathology and Laboratory Medicine
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Amphipols stabilize the Chlamydia major outer membrane protein and enhance its protective ability as a vaccine.
Vaccine Jun, 2011 | Pubmed ID: 21550371
Toll-like receptor 2-dependent activity of native major outer membrane protein proteosomes of Chlamydia trachomatis.
Infection and immunity Jan, 2013 | Pubmed ID: 23132491
Vaccination with the recombinant major outer membrane protein elicits antibodies to the constant domains and induces cross-serovar protection against intranasal challenge with Chlamydia trachomatis.
Infection and immunity May, 2013 | Pubmed ID: 23478318
Vaccination with major outer membrane protein proteosomes elicits protection in mice against a Chlamydia respiratory challenge.
Microbes and infection Nov, 2013 | Pubmed ID: 23999313
Increased immunoaccessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with Chlamydia muridarum.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2014 | Pubmed ID: 24778450
Computational modeling of TC0583 as a putative component of the Chlamydia muridarum V-type ATP synthase complex and assessment of its protective capabilities as a vaccine antigen.
Microbes and infection Apr, 2016 | Pubmed ID: 26706820
The cationic liposomal adjuvants CAF01 and CAF09 formulated with the major outer membrane protein elicit robust protection in mice against a Chlamydia muridarum respiratory challenge.
Vaccine 03, 2017 | Pubmed ID: 28238632
Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C. muridarum challenge.
Vaccine 05, 2017 | Pubmed ID: 28385608
Transcervical Inoculation with Chlamydia trachomatis Induces Infertility in HLA-DR4 Transgenic and Wild-Type Mice.
Infection and immunity 01, 2018 | Pubmed ID: 29038126
Co-delivery of amphipol-conjugated adjuvant with antigen, and adjuvant combinations, enhance immune protection elicited by a membrane protein-based vaccine against a mucosal challenge with Chlamydia.
Vaccine 10, 2018 | Pubmed ID: 30293763
Characterization of the Horizontal and Vertical Sexual Transmission of Genital Infections in a New Mouse Model.
Infection and immunity 07, 2019 | Pubmed ID: 30833332
A Recombinant Chlamydia trachomatis MOMP Vaccine Elicits Cross-serogroup Protection in Mice Against Vaginal Shedding and Infertility.
The Journal of infectious diseases 01, 2020 | Pubmed ID: 31504647
Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR.
Lab on a chip 02, 2020 | Pubmed ID: 31872202
Protection of outbred mice against a vaginal challenge by a serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant.
Human vaccines & immunotherapeutics 10, 2020 | Pubmed ID: 32118511
Improved protection against Chlamydia muridarum using the native major outer membrane protein trapped in Resiquimod-carrying amphipols and effects in protection with addition of a Th1 (CpG-1826) and a Th2 (Montanide ISA 720) adjuvant.
Vaccine 06, 2020 | Pubmed ID: 32386746
Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the major outer membrane protein variable domains using the porin B as a scaffold.
NPJ vaccines , 2020 | Pubmed ID: 32411400
Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from infected cells.
NPJ vaccines , 2020 | Pubmed ID: 33014435
Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a genital challenge.
NPJ vaccines , 2020 | Pubmed ID: 33083025
Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score.
mSphere 04, 2021 | Pubmed ID: 33910993
Genome-Wide B Cell, CD4, and CD8 T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines.
Journal of immunology (Baltimore, Md. : 1950) 06, 2021 | Pubmed ID: 33911008
Induction of Protection in Mice against a Respiratory Challenge by a Vaccine Formulated with the Major Outer Membrane Protein in Nanolipoprotein Particles.
Vaccines Jul, 2021 | Pubmed ID: 34358171
Disruption of β-Catenin-Dependent Wnt Signaling in Colon Cancer Cells Remodels the Microenvironment to Promote Tumor Invasion.
Molecular cancer research : MCR Mar, 2022 | Pubmed ID: 34799404