Stem Cell Therapies in Neurodegenerative Diseases Lab
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Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells.
Stem cells and development Nov, 2010 | Pubmed ID: 20521974
Transplanted oligodendrocytes and motoneuron progenitors generated from human embryonic stem cells promote locomotor recovery after spinal cord transection.
Stem cells (Dayton, Ohio) Sep, 2010 | Pubmed ID: 20665739
Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells.
Frontiers in genetics , 2014 | Pubmed ID: 24860598
Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation.
Scientific reports Apr, 2015 | Pubmed ID: 25860664
Human iPSC derived disease model of MERTK-associated retinitis pigmentosa.
Scientific reports Aug, 2015 | Pubmed ID: 26263531
Connexin 50 Expression in Ependymal Stem Progenitor Cells after Spinal Cord Injury Activation.
International journal of molecular sciences Nov, 2015 | Pubmed ID: 26561800
Stem Cells and Labeling for Spinal Cord Injury.
International journal of molecular sciences Dec, 2016 | Pubmed ID: 28035961
Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal-Free Conditions.
Stem cells translational medicine 04, 2017 | Pubmed ID: 28213969
hiPSC Disease Modeling of Rare Hereditary Cerebellar Ataxias: Opportunities and Future Challenges.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 10, 2017 | Pubmed ID: 28281409
Generation of a human iPSC line from a patient with retinitis pigmentosa caused by mutation in PRPF8 gene.
Stem cell research 05, 2017 | Pubmed ID: 28677533
Stem Cell-Based Therapy in Transplantation and Immune-Mediated Diseases.
Stem cells international , 2017 | Pubmed ID: 29018485
FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury.
International journal of molecular sciences Jan, 2018 | Pubmed ID: 29315225
Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa.
Stem cells (Dayton, Ohio) 04, 2018 | Pubmed ID: 29345014
Generation of a human iPSC line from a patient with congenital glaucoma caused by mutation in CYP1B1 gene.
Stem cell research 04, 2018 | Pubmed ID: 29453128
Generation of a human iPSC line by mRNA reprogramming.
Stem cell research 04, 2018 | Pubmed ID: 29499498
Corrigendum to Generation of a human iPSC line by mRNA reprogramming. Stem Cell Res., Volume 28, April 2018, Pages 157-160.
Stem cell research 08, 2018 | Pubmed ID: 30015172
Generation of a human iPSC line from a patient with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) caused by mutation in SACSIN gene.
Stem cell research 08, 2018 | Pubmed ID: 30144656
Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury.
Results and problems in cell differentiation , 2018 | Pubmed ID: 30209655
Generation of a human iPSC line from a patient with Leber congenital amaurosis caused by mutation in AIPL1.
Stem cell research 12, 2018 | Pubmed ID: 30366342
Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene.
Stem cell research 12, 2018 | Pubmed ID: 30384130
Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs*5 mutation in MERTK.
Stem cell research 01, 2019 | Pubmed ID: 30612079
The identification of small molecules that stimulate retinal pigment epithelial cells: potential novel therapeutic options for treating retinopathies.
Expert opinion on drug discovery 02, 2019 | Pubmed ID: 30616395
Assessment of Toxic Effects of Ochratoxin A in Human Embryonic Stem Cells.
Toxins 04, 2019 | Pubmed ID: 30974856
Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling.
Stem cell research 07, 2019 | Pubmed ID: 31082679
Deciphering retinal diseases through the generation of three dimensional stem cell-derived organoids: Concise Review.
Stem cells (Dayton, Ohio) 12, 2019 | Pubmed ID: 31617949
Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal.
Molecular vision , | Pubmed ID: 31814692
Organized Neurogenic-Niche-Like Pinwheel Structures Discovered in Spinal Cord Tissue-Derived Neurospheres.
Frontiers in cell and developmental biology , 2019 | Pubmed ID: 31921846
Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1.
Scientific reports , | Pubmed ID: 32214115
Glaucoma as a Neurodegenerative Disease Caused by Intrinsic Vulnerability Factors.
Progress in neurobiology 10, 2020 | Pubmed ID: 32360241
Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 01, 2021 | Pubmed ID: 33000422
Unraveling the Developmental Roadmap toward Human Brown Adipose Tissue.
Stem cell reports 03, 2021 | Pubmed ID: 33606988
Gene Correction Recovers Phagocytosis in Retinal Pigment Epithelium Derived from Retinitis Pigmentosa-Human-Induced Pluripotent Stem Cells.
International journal of molecular sciences 02, 2021 | Pubmed ID: 33672445
Mutant PRPF8 Causes Widespread Splicing Changes in Spliceosome Components in Retinitis Pigmentosa Patient iPSC-Derived RPE Cells.
Frontiers in neuroscience , 2021 | Pubmed ID: 33994920
Subretinal Implantation of Human Primary RPE Cells Cultured on Nanofibrous Membranes in Minipigs.
Biomedicines Mar, 2022 | Pubmed ID: 35327471
Lyubomyr Lytvynchuk*,1,2,
Zbynek Stranak*,3,
Hana Studenovska4,
David Rais4,
Štěpán Popelka4,
Lucie Tichotová5,6,
Yaroslav Nemesh5,6,
Anastasiia Kolesnikova5,6,
Ruslan Nyshchuk5,6,
Anna Brymová5,6,
Zdeňka Ellederová5,
Jana Čížková5,
Jana Juhásová5,
Štefan Juhás5,
Pavla Jendelová7,
Richárd Nagymihály8,
Igor Kozak9,
Slaven Erceg10,
Susanne Binder11,
Brigitte Müller1,
Knut Stieger1,
Jan Motlik5,
Goran Petrovski*,8,
Taras Ardan*,5
1Eye Clinic, Department of Ophthalmology, University Hospital Giessen and Marburg GmbH,
2, Karl Landsteiner Institute for Retinal Research and Imaging,
3Department of Ophthalmology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague,
4Institute of Macromolecular Chemistry, Czech Academy of Sciences,
5Institute of Animal Physiology and Genetics, Czech Academy of Sciences,
6Department of Cell Biology, Faculty of Science, Charles University,
7Institute of Experimental Medicine, Czech Academy of Sciences,
8Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Oslo,
9, Moorfields Eye Hospitals UAE,
10Stem Cell Therapies in Neurodegenerative Diseases Lab, Research Center “Principe Felipe”,
11Eye Center Donaustadt, Department of Ophthalmology, Sigmund Freud University