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Department of Neurology,
Department of Neuroscience
Sreeganga S. Chandra has not added Biography.
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αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2010 | Pubmed ID: 20974939
Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2011 | Pubmed ID: 21593311
Identification of CSPα clients reveals a role in dynamin 1 regulation.
Neuron Apr, 2012 | Pubmed ID: 22500636
Monomeric synucleins generate membrane curvature.
The Journal of biological chemistry Jan, 2013 | Pubmed ID: 23184946
Synucleins regulate the kinetics of synaptic vesicle endocytosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2014 | Pubmed ID: 25009269
Oligomerization of Cysteine String Protein alpha mutants causing adult neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta Nov, 2014 | Pubmed ID: 25064588
Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation.
Acta neuropathologica Apr, 2016 | Pubmed ID: 26659577
Synucleins Have Multiple Effects on Presynaptic Architecture.
Cell reports 01, 2017 | Pubmed ID: 28052246
Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 10, 2017 | Pubmed ID: 28847804
Role of the endolysosomal system in Parkinson's disease.
Journal of neurochemistry 09, 2019 | Pubmed ID: 31287913
A model of neuronal ceroid lipofuscinosis reveals a hypermorphic gain of function mechanism.
eLife 10, 2019 | Pubmed ID: 31663851
Hsp110 mitigates α-synuclein pathology in vivo.
Proceedings of the National Academy of Sciences of the United States of America 11, 2019 | Pubmed ID: 31685606
Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.
PLoS biology 03, 2022 | Pubmed ID: 35358180
A Markov random field model-based approach for differentially expressed gene detection from single-cell RNA-seq data.
Briefings in bioinformatics May, 2022 | Pubmed ID: 35514182
Yale University
Sofia Massaro Tieze1,2,3,
Sreeganga S. Chandra1,2,
D. J. Vidyadhara1,2
1Department of Neurology, Yale University,
2Department of Neuroscience, Yale University,
3Interdepartmental Neuroscience Program, Yale University
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