Center for Molecular Medicine-Cell Biology,
University Medical Center Utrecht,
Center for Molecular Medicine-Cell Biology, University Medical Center Utrecht
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Synaptic vesicles form by budding from tubular extensions of sorting endosomes in PC12 cells.
Molecular biology of the cell Dec, 1999 | Pubmed ID: 10588650
A phosphorylation site regulates sorting of the vesicular acetylcholine transporter to dense core vesicles.
The Journal of cell biology Apr, 2000 | Pubmed ID: 10769030
Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes.
Traffic (Copenhagen, Denmark) Aug, 2003 | Pubmed ID: 12839498
Aberrant receptor-mediated endocytosis of Schistosoma mansoni glycoproteins on host lipoproteins.
PLoS medicine Aug, 2006 | Pubmed ID: 16942390
Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2006 | Pubmed ID: 17101973
Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure.
Molecular biology of the cell Apr, 2007 | Pubmed ID: 17251550
Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis.
The Journal of cell biology Oct, 2007 | Pubmed ID: 17923531
Glycolipid-dependent sorting of melanosomal from lysosomal membrane proteins by lumenal determinants.
Traffic (Copenhagen, Denmark) Jun, 2008 | Pubmed ID: 18373728
Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2009 | Pubmed ID: 19805154
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.
PLoS biology Jan, 2010 | Pubmed ID: 20098723
A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells.
Hepatology (Baltimore, Md.) Jun, 2010 | Pubmed ID: 20512993
Architecture of the mammalian Golgi.
Cold Spring Harbor perspectives in biology Jul, 2011 | Pubmed ID: 21502307
HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets.
Assay and drug development technologies Oct, 2016 | Pubmed ID: 27636821
Molecular Pathway of Microtubule Organization at the Golgi Apparatus.
Developmental cell Oct, 2016 | Pubmed ID: 27666745
Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform.
Assay and drug development technologies Oct, 2016 | Pubmed ID: 27732064
EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.
The Journal of cell biology Oct, 2017 | Pubmed ID: 28814570
Improving Comprehension Efficiency of High Content Screening Data Through Interactive Visualizations.
Assay and drug development technologies , 2017 | Pubmed ID: 28837357
Ultrastructural Characterization of Membrane Rearrangements Induced by Porcine Epidemic Diarrhea Virus Infection.
Viruses Sep, 2017 | Pubmed ID: 28872588
Single organelle dynamics linked to 3D structure by correlative live-cell imaging and 3D electron microscopy.
Traffic (Copenhagen, Denmark) May, 2018 | Pubmed ID: 29451726
Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration .
Theranostics , 2018 | Pubmed ID: 29463990
Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions.
Nature communications Feb, 2018 | Pubmed ID: 29476049
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.
Nature cell biology , | Pubmed ID: 29915359
Fluorescently Labelled Silica Coated Gold Nanoparticles as Fiducial Markers for Correlative Light and Electron Microscopy.
Scientific reports Sep, 2018 | Pubmed ID: 30206379
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Neuron Dec, 2018 | Pubmed ID: 30392797
The 2018 correlative microscopy techniques roadmap.
Journal of physics D: Applied physics Nov, 2018 | Pubmed ID: 30799880
High accuracy, fiducial marker-based image registration of correlative microscopy images.
Scientific reports Mar, 2019 | Pubmed ID: 30824844
Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy.
Scientific reports May, 2019 | Pubmed ID: 31061420
CORVET, CHEVI and HOPS - multisubunit tethers of the endo-lysosomal system in health and disease.
Journal of cell science May, 2019 | Pubmed ID: 31092635
The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.
JCI insight Jun, 2019 | Pubmed ID: 31167970
DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells.
Journal of lipid research Oct, 2019 | Pubmed ID: 31315900
The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage.
EMBO reports Oct, 2019 | Pubmed ID: 31432621
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
eLife Dec, 2019 | Pubmed ID: 31868166
Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.
SLAS discovery : advancing life sciences R & D Jul, 2020 | Pubmed ID: 32400262
Integrated super resolution fluorescence microscopy and transmission electron microscopy.
Ultramicroscopy Aug, 2020 | Pubmed ID: 32470633
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Life science alliance Sep, 2020 | Pubmed ID: 32665377
Quantifying lymphocyte vacuolization serves as a measure of CLN3 disease severity.
JIMD reports Jul, 2020 | Pubmed ID: 32685355
Wiskott-Aldrich syndrome protein restricts cGAS/STING activation by dsDNA immune complexes.
JCI insight Sep, 2020 | Pubmed ID: 32721945
Apolipoprotein L1-Specific Antibodies Detect Endogenous APOL1 inside the Endoplasmic Reticulum and on the Plasma Membrane of Podocytes.
Journal of the American Society of Nephrology : JASN 09, 2020 | Pubmed ID: 32764142
Pancreatic β-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion.
Diabetes Feb, 2021 | Pubmed ID: 33168621
Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation.
EMBO molecular medicine May, 2021 | Pubmed ID: 33851776
Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis.
EMBO molecular medicine Jul, 2021 | Pubmed ID: 34165243
Understanding membrane traffic from molecular ensemble, energetics, and the cell biology of participant components.
Current opinion in cell biology Aug, 2021 | Pubmed ID: 34219001
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.
PLoS biology Jul, 2021 | Pubmed ID: 34283825
ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability.
Nature communications Jul, 2021 | Pubmed ID: 34301956
Author Correction: Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions.
Nature communications Sep, 2021 | Pubmed ID: 34588435
The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism.
Journal of inherited metabolic disease Mar, 2022 | Pubmed ID: 34671987
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins.
The Journal of cell biology Jan, 2022 | Pubmed ID: 34817533
High Resolution Proteomic Analysis of Subcellular Fractionated Boar Spermatozoa Provides Comprehensive Insights Into Perinuclear Theca-Residing Proteins.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35252197
FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer.
Cell reports Apr, 2022 | Pubmed ID: 35385742
An optimized protocol for immuno-electron microscopy of endogenous LC3.
Autophagy Apr, 2022 | Pubmed ID: 35387562
Correlative Organelle Microscopy: Fluorescence Guided Volume Electron Microscopy of Intracellular Processes.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35478966
Bimodal endocytic probe for three-dimensional correlative light and electron microscopy.
Cell reports methods May, 2022 | Pubmed ID: 35637912
Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.
Frontiers in endocrinology , 2022 | Pubmed ID: 35966052