Dmitri B. Papkovsky

Spectral-luminescent study of the porphyrin-diketones and their complexes.

Synthesis and evaluation of phosphorescent oligonucleotide probes for hybridisation assays.

Fluorescence-based cell viability screening assays using water-soluble oxygen probes.

Evaluation of the phosphorescent palladium(II)-coproporphyrin labels in separation-free hybridization assays.

Homogeneous assays for cellular proteases employing the platinum(II)-coproporphyrin label and time-resolved phosphorescence.

Optical oxygen microrespirometry as a platform for environmental toxicology and animal model studies.

Emerging applications of phosphorescent metalloporphyrins.

Fluorescence based oxygen uptake analysis in the study of metabolic responses to apoptosis induction.

The use of a fluorescence-based oxygen uptake assay in the analysis of cytotoxicity.

Rapid high-throughput assessment of aerobic bacteria in complex samples by fluorescence-based oxygen respirometry.

Sensing intracellular oxygen using near-infrared phosphorescent probes and live-cell fluorescence imaging.

Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates.

Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission.

Toxicological profiling of chemical and environmental samples using panels of test organisms and optical oxygen respirometry.

PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.

In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay.

Analysis of activity and inhibition of oxygen-dependent enzymes by optical respirometry on the LightCycler system.

Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides.

Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells.

Phosphorescent oxygen sensors based on nanostructured polyolefin substrates.

Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange.

Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique.

Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria.

Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor.

Intracellular O2 sensing probe based on cell-penetrating phosphorescent nanoparticles.

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival.

Cell-penetrating conjugates of coproporphyrins with oligoarginine peptides: rational design and application for sensing intracellular O2.

Optical probes and techniques for O2 measurement in live cells and tissue.

Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes.

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization.

Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling.

Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae.

Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.

In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe.

Biological detection by optical oxygen sensing.

Measurement of cell respiration and oxygenation in standard multichannel biochips using phosphorescent O2-sensitive probes.

Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling.

Imaging of neurosphere oxygenation with phosphorescent probes.

Oxygen-sensitive phosphorescent nanomaterials produced from high-density polyethylene films by local solvent-crazing.

Kinetic analysis of local oxygenation and respiratory responses of mammalian cells using intracellular oxygen-sensitive probes and time-resolved fluorometry.

Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles.

Comparison of the three optical platforms for measurement of cellular respiration.

Multi-parametric O₂ imaging in three-dimensional neural cell models with the phosphorescent probes.

Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling.

In vitro ischemia decreases histone H4K16 acetylation in neural cells.

Cell energy budget platform for assessment of cell metabolism.

Oxygen-sensing scaffolds for 3-dimensional cell and tissue culture.

Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models.

Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes.

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression.

Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis.

Metallochelate Coupling of Phosphorescent Pt-Porphyrins to Peptides, Proteins, and Self-Assembling Protein Nanoparticles.

The Ca2+/Mn2+-transporting SPCA2 pump is regulated by oxygen and cell density in colon cancer cells.

An Assessment of the Influence of the Industry Distribution Chain on the Oxygen Levels in Commercial Modified Atmosphere Packaged Cheddar Cheese Using Non-Destructive Oxygen Sensor Technology.

Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue.

Sulforhodamine Nanothermometer for Multiparametric Fluorescence Lifetime Imaging Microscopy.

Phosphorescence based O sensors - Essential tools for monitoring cell and tissue oxygenation and its impact on metabolism.

Cellular ROS imaging with hydro-Cy3 dye is strongly influenced by mitochondrial membrane potential.

Use of Fluorescence Lifetime Imaging Microscopy (FLIM) as a Timer of Cell Cycle S Phase.

Low energy costs of F1Fo ATP synthase reversal in colon carcinoma cells deficient in mitochondrial complex IV.

Planar implantable sensor for in vivo measurement of cellular oxygen metabolism in brain tissue.

Assessment and Use of Optical Oxygen Sensors as Tools to Assist in Optimal Product Component Selection for the Development of Packs of Ready-to-Eat Mixed Salads and for the Non-Destructive Monitoring of in-Pack Oxygen Levels Using Chilled Storage.

Use of Optical Oxygen Sensors in Non-Destructively Determining the Levels of Oxygen Present in Combined Vacuum and Modified Atmosphere Packaged Pre-Cooked Convenience-Style Foods and the Use of Ethanol Emitters to Extend Product Shelf-Life.

Steering surface topographies of electrospun fibers: understanding the mechanisms.

Phosphorescent Oxygen and Mechanosensitive Nanostructured Materials Based on Hard Elastic Polypropylene Films.

Single-cell time-lapse imaging of intracellular O in response to metabolic inhibition and mitochondrial cytochrome-c release.

Insulin-like growth factor 1 signaling is essential for mitochondrial biogenesis and mitophagy in cancer cells.

Live cell imaging of mouse intestinal organoids reveals heterogeneity in their oxygenation.

Multi-Parametric Imaging of Hypoxia and Cell Cycle in Intestinal Organoid Culture.

Intracellular probes for imaging oxygen concentration: how good are they?

Assessment of Performance of the Industrial Process of Bulk Vacuum Packaging of Raw Meat with Nondestructive Optical Oxygen Sensing Systems.

Imaging of oxygen and hypoxia in cell and tissue samples.

Cellulose-based scaffolds for fluorescence lifetime imaging-assisted tissue engineering.

Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models and .

Estimation of the Mitochondrial Membrane Potential Using Fluorescence Lifetime Imaging Microscopy.

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses.

Small molecule phosphorescent probes for O imaging in 3D tissue models.

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.

Translation initiation downstream from annotated start codons in human mRNAs coevolves with the Kozak context.

Visualization of Stem Cell Niche by Fluorescence Lifetime Imaging Microscopy.

Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.

Unusually efficient CUG initiation of an overlapping reading frame in mRNA yields novel protein POLGARF.

Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.

Mapping O concentration in ex-vivo tissue samples on a fast PLIM macro-imager.

Facile biosensor-based system for on-site quantification of total viable counts in food and environmental swabs.

Cell Energy Budget Platform for Multiparametric Assessment of Cell and Tissue Metabolism.

A Simple Sensor System for Onsite Monitoring of O in Vacuum-Packed Meats during the Shelf Life.

A sensor-based system for rapid on-site testing of microbial contamination in meat samples and carcasses.

Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.

Ghrelin rapidly elevates protein synthesis in vitro by employing the rpS6K-eEF2K-eEF2 signalling axis.

Heterosubstituted Derivatives of PtPFPP for O Sensing and Cell Analysis: Structure-Activity Relationships.