Nissi M. Varki

Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.

Heparin inhibition of selectin-mediated interactions during the hematogenous phase of carcinoma metastasis: rationale for clinical studies in humans.

Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.

Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation.

Human-specific regulation of alpha 2-6-linked sialic acids.

Increase in expression of the copper transporter ATP7A during platinum drug-based treatment is associated with poor survival in ovarian cancer patients.

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification.

Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies.

A fluorescent orthotopic mouse model for reliable measurement and genetic modulation of human neuroblastoma metastasis.

Combining Parenting and a Science Career.

Combining parenting and a science career.

A human-specific gene in microglia.

L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest.

Expression of the human copper influx transporter 1 in normal and malignant human tissues.

Diversity in cell surface sialic acid presentations: implications for biology and disease.

alpha 2-6-Linked sialic acids on N-glycans modulate carcinoma differentiation in vivo.

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin.

Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression.

Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products.

Molecular basis of metastasis.

A dietary non-human sialic acid may facilitate hemolytic-uremic syndrome.

Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium.

The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.

Biomedical differences between human and nonhuman hominids: potential roles for uniquely human aspects of sialic acid biology.

Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.

Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: MECHANISMS UNDERLYING GASTROINTESTINAL INCORPORATION OF THE NON-HUMAN SIALIC ACID XENO-AUTOANTIGEN N-GLYCOLYLNEURAMINIC ACID.