Nicholas Arpaia

Clonal Bifurcation of Foxp3 Expression Visualized in Thymocytes and T Cells.

Treg Cells: A LAGging Hand Holds the Double-Edged Sword of the IL-23 Axis.

Glycans for good.

Programmable bacteria induce durable tumor regression and systemic antitumor immunity.

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies.

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts.

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.

CXCL13 shapes tertiary lymphoid structures and promotes response to immunotherapy in bladder cancer.

The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.

A programmable encapsulation system improves delivery of therapeutic bacteria in mice.

BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer.

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.

Engineering bacteria as interactive cancer therapies.

Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells.

Dietary tryptophan deficiency promotes gut RORγt Treg cells at the expense of Gata3 Treg cells and alters commensal microbiota metabolism.

Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity.

Neo-Adjuvant immunotherapies: Bladder cancer as a platform for drug development targeting mucosal immunity.

Probiotic-guided CAR-T cells for solid tumor targeting.

Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.