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Department of Immunology
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Time-dependent expression of heat shock proteins 70 and 90 in tissues of the anoxic western painted turtle.
The Journal of experimental biology Oct, 2004 | Pubmed ID: 15371485
Bacterial infection and tissue-specific Hsp72, -73 and -90 expression in western painted turtles.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP Jun, 2004 | Pubmed ID: 15450861
Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.
Immunity Dec, 2015 | Pubmed ID: 26682987
Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis.
Acta neuropathologica Apr, 2018 | Pubmed ID: 29441412
Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.
Acta neuropathologica communications May, 2018 | Pubmed ID: 29724241
Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in and Mice.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2018 | Pubmed ID: 29980612
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
Cell Jan, 2019 | Pubmed ID: 30612739
Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry.
eLife Aug, 2019 | Pubmed ID: 31368890
Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2019 | Pubmed ID: 31641069
Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury.
JCI insight Jan, 2020 | Pubmed ID: 31821174
The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates.
The Journal of biological chemistry Nov, 2020 | Pubmed ID: 33168630
Gut microbiota-specific IgA B cells traffic to the CNS in active multiple sclerosis.
Science immunology Nov, 2020 | Pubmed ID: 33219152
Stromal Cell-Mediated Coordination of Immune Cell Recruitment, Retention, and Function in Brain-Adjacent Regions.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2021 | Pubmed ID: 33397742
An "Outside-In" and "Inside-Out" Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases.
Frontiers in cellular neuroscience , 2020 | Pubmed ID: 33488361
The Ins and Outs of Central Nervous System Inflammation-Lessons Learned from Multiple Sclerosis.
Annual review of immunology Apr, 2021 | Pubmed ID: 33524273
Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory.
Acta neuropathologica Oct, 2021 | Pubmed ID: 34170374
CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2021 | Pubmed ID: 34400521
Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis.
JCI insight Mar, 2022 | Pubmed ID: 35104246
Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation.
JCI insight Jun, 2022 | Pubmed ID: 35536649
Age-related changes in multiple sclerosis and experimental autoimmune encephalomyelitis.
Seminars in immunology Jan, 2022 | Pubmed ID: 35752572
University of Toronto
Carmen C. Ucciferri1,
Annette Gower2,
Nuria Alvarez-Sanchez1,2,
Heather Whetstone3,
Valeria Ramaglia1,
Jennifer L. Gommerman1,
Koroboshka Brand-Arzamendi2,
Raphael Schneider2,4,
Shannon E Dunn1,2,5
1Department of Immunology, University of Toronto,
2, Keenan Research Centre for Biomedical Science of St. Michael’s Hospital,
3Sickkids Research Institute, The Hospital for Sick Children,
4BARLO MS Centre, St. Michael’s Hospital,
5Women’s College Research Institute, Women’s College Hospital
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