The Lab of Aging Research,
State Key Laboratory of Biotherapy,
National Clinical Research Center for Geriatrics,
West China Hospital,
The Lab of Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital
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Pro12Ala polymorphism in PPAR gamma 2 associated with essential hypertension in Chinese nonagenarians/centenarians.
Experimental gerontology Dec, 2008 | Pubmed ID: 18789381
[Effect of total flavonoids of Hippophae rhamnoides L. on the expression of MCP-1 in aorta of spontaneously hypertensive rats].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition May, 2009 | Pubmed ID: 19627010
[Construction of eukaryotic expression plasmid for a novel zinc finger protein gene Zfp637 and its effect on breast carcinoma cell EMT6].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Jul, 2009 | Pubmed ID: 19764547
A novel zinc finger protein Zfp637 behaves as a repressive regulator in myogenic cellular differentiation.
Journal of cellular biochemistry May, 2010 | Pubmed ID: 20235149
Chromatin accessibility and transcription factor binding at the PPARγ2 promoter during adipogenesis is protein kinase A-dependent.
Journal of cellular physiology Jan, 2011 | Pubmed ID: 20625991
D-galactose induces necroptotic cell death in neuroblastoma cell lines.
Journal of cellular biochemistry Dec, 2011 | Pubmed ID: 21826710
High throughput screening technology and the small molecules modulating aging related signals.
Combinatorial chemistry & high throughput screening Mar, 2012 | Pubmed ID: 22221057
Anti-tumour strategies aiming to target tumour-associated macrophages.
Immunology Feb, 2013 | Pubmed ID: 23113570
Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes.
Lipids in health and disease Jul, 2013 | Pubmed ID: 23866690
The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice.
Antioxidants & redox signaling Feb, 2014 | Pubmed ID: 23875776
Methods of cellular senescence induction using oxidative stress.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23929103
The combinational effect of vincristine and berberine on growth inhibition and apoptosis induction in hepatoma cells.
Journal of cellular biochemistry Apr, 2014 | Pubmed ID: 24243568
The PPARγ locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner.
PloS one , 2014 | Pubmed ID: 24465921
Imperialine and Verticinone from Bulbs of Fritillaria wabuensis Inhibit Pro-inflammatory Mediators in LPS-stimulated RAW 264.7 Macrophages.
Planta medica Jul, 2015 | Pubmed ID: 26132855
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Jan, 2016 | Pubmed ID: 26799652
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.
Aging cell Jun, 2016 | Pubmed ID: 26890602
Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet.
PloS one , 2016 | Pubmed ID: 26963814
PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation.
Autophagy Sep, 2016 | Pubmed ID: 27305174
Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence.
Autophagy Jan, 2017 | Pubmed ID: 27791464
Simultaneous enhancement of cellular and humoral immunity by the high salt formulation of Al(OH) adjuvant.
Cell research Apr, 2017 | Pubmed ID: 28106074
FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis.
Cell death & disease Mar, 2017 | Pubmed ID: 28333151
Protein kinase Cβ activates fat mass and obesity-associated protein by influencing its ubiquitin/proteasome degradation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2017 | Pubmed ID: 28626026
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
Journal of cellular physiology May, 2018 | Pubmed ID: 28884830
Mitochondrial dysfunction and chronic lung disease.
Cell biology and toxicology Dec, 2019 | Pubmed ID: 31119467
Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress-induced senescence.
The Journal of biological chemistry Apr, 2020 | Pubmed ID: 32047109
Nrf2-SHP Cascade-Mediated STAT3 Inactivation Contributes to AMPK-Driven Protection Against Endotoxic Inflammation.
Frontiers in immunology , 2020 | Pubmed ID: 32210977
The Implication of Oxidative Stress and AMPK-Nrf2 Antioxidative Signaling in Pneumonia Pathogenesis.
Frontiers in endocrinology , 2020 | Pubmed ID: 32625169
Surmounting cancer drug resistance: New insights from the perspective of N-methyladenosine RNA modification.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy Dec, 2020 | Pubmed ID: 32892147
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy Feb, 2021 | Pubmed ID: 33634751
Nrf2 signalling pathway and autophagy impact on the preventive effect of green tea extract against alcohol-induced liver injury.
The Journal of pharmacy and pharmacology Jun, 2021 | Pubmed ID: 33877365
Microphthalmia-Associated Transcription Factor in Senescence and Age-Related Diseases.
Gerontology , 2021 | Pubmed ID: 33940580
Independent and opposing associations of dietary phytosterols intake and PLCE1 rs2274223 polymorphisms on esophageal squamous cell carcinoma risk.
European journal of nutrition Dec, 2021 | Pubmed ID: 34046701
Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Cellular and molecular life sciences : CMLS Dec, 2021 | Pubmed ID: 34689235
Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells.
MedComm Jun, 2021 | Pubmed ID: 34766147
miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD/SIRT inactivation.
Signal transduction and targeted therapy Mar, 2022 | Pubmed ID: 35241643
Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling.
Biochemical pharmacology Jun, 2022 | Pubmed ID: 35439535
Gut Microbiota Interact With the Brain Through Systemic Chronic Inflammation: Implications on Neuroinflammation, Neurodegeneration, and Aging.
Frontiers in immunology , 2022 | Pubmed ID: 35464431
The relationship between disaster preparedness, psychological capital, and coping style among nurses: A cross-sectional study from China.
Perspectives in psychiatric care Oct, 2022 | Pubmed ID: 35478409
SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production.
Cell reports May, 2022 | Pubmed ID: 35508129
SeHed, a novel gene expression system with stress-evoked hydrogen peroxide elimination property and anti-aging effect.
Signal transduction and targeted therapy Jul, 2022 | Pubmed ID: 35835764
Acute iron overload aggravates blood-brain barrier disruption and hemorrhagic transformation after transient focal ischemia in rats with hyperglycemia.
IBRO neuroscience reports Dec, 2022 | Pubmed ID: 35847179
Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.
Frontiers in pharmacology , 2022 | Pubmed ID: 35860029
APPL1 Is a Prognostic Biomarker and Correlated with Treg Cell Infiltration via Oxygen-Consuming Metabolism in Renal Clear Cell Carcinoma.
Oxidative medicine and cellular longevity , 2023 | Pubmed ID: 36846720
Protein-level mutant p53 reporters identify druggable rare precancerous clones in noncancerous tissues.
Nature cancer Aug, 2023 | Pubmed ID: 37537298
CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology.
Journal of translational medicine Jan, 2024 | Pubmed ID: 38216965
AMPK-upregulated microRNA-708 plays as a suppressor of cellular senescence and aging via downregulating disabled-2 and mTORC1 activation.
MedComm Mar, 2024 | Pubmed ID: 38463393
mTORC2: A neglected player in aging regulation.
Journal of cellular physiology Jul, 2024 | Pubmed ID: 38982866
1Institute of Hematology, Department of Hematology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University,
2The Lab of Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University,
3Precision Medicine Research Laboratory, West China Hospital, Sichuan University