Uwe Himmelreich

Cerebral nocardiosis characterized by magnetic resonance spectroscopy in vivo.

Heart design: free ADP scales with absolute mitochondrial and myofibrillar volumes from mouse to human.

Isolation and characterization of capsule structure mutant strains of Cryptococcus neoformans.

Pathology of hepatocellular carcinoma and its precursors using proton magnetic resonance spectroscopy and a statistical classification strategy.

Metabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil function.

Pathology of Barrett's esophagus by proton magnetic resonance spectroscopy and a statistical classification strategy.

Identification of metabolites of importance in the pathogenesis of pulmonary cryptococcoma using nuclear magnetic resonance spectroscopy.

Detergent-resistant membrane fractions contribute to the total 1H NMR-visible lipid signal in cells.

Pathologic characterization of human prostate tissue with proton MR spectroscopy.

Rapid identification of Candida species by using nuclear magnetic resonance spectroscopy and a statistical classification strategy.

Determination of grade and receptor status from the primary breast lesion by magnetic resonance spectroscopy.

Cas3p belongs to a seven-member family of capsule structure designer proteins.

Identification of Staphylococcus aureus brain abscesses: rat and human studies with 1H MR spectroscopy.

Diagnosis of cerebral cryptococcoma using a computerized analysis of 1H NMR spectra in an animal model.

Improved stem cell MR detectability in animal models by modification of the inhalation gas.

A rapid screening test to distinguish between Candida albicans and Candida dubliniensis using NMR spectroscopy.

Magnetic resonance spectroscopy detects biochemical changes in the brain associated with chronic low back pain: a preliminary report.

Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis.

Antifungal effects on metabolite profiles of medically important yeast species measured by nuclear magnetic resonance spectroscopy.

Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.

Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene.

Switching on the lights for gene therapy.

Cell tracking using magnetic resonance imaging.

Normal brain cells contribute to the bystander effect in suicide gene therapy of malignant glioma.

Molecular and cellular MR imaging: potentials and challenges for neurological applications.

Stem cell labeling for magnetic resonance imaging.

Multimodal imaging of neural progenitor cell fate in rodents.

Cell labeling and tracking for experimental models using magnetic resonance imaging.

Rapid etiological classification of meningitis by NMR spectroscopy based on metabolite profiles and host response.

A comparison of random forest and its Gini importance with standard chemometric methods for the feature selection and classification of spectral data.

The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii.

Effects of MRI contrast agents on the stem cell phenotype.

Pathogenesis of pulmonary Cryptococcus gattii infection: a rat model.

Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2.

Age-associated adaptations in murine adipose tissues.

Characterization of the inflammatory response in a photothrombotic stroke model by MRI: implications for stem cell transplantation.

Intracellular nanoparticle coating stability determines nanoparticle diagnostics efficacy and cell functionality.

Cytotoxic effects of iron oxide nanoparticles and implications for safety in cell labelling.

Impact of clock gene Bmal1 deficiency on nutritionally induced obesity in mice.

MR perfusion and diffusion imaging in the follow-up of recurrent glioblastoma treated with dendritic cell immunotherapy: a pilot study.

The labeling of cationic iron oxide nanoparticle-resistant hepatocellular carcinoma cells using targeted magnetoliposomes.

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes.

Site-specific 68Ga-labeled Annexin A5 as a PET imaging agent for apoptosis.

Polyelectrolyte coating of iron oxide nanoparticles for MRI-based cell tracking.

(19)F-heptuloses as tools for the non-invasive imaging of GLUT2-expressing cells.

A review on various targeted anticancer therapies.

Gliomas: diffusion kurtosis MR imaging in grading.

In vivo imaging of inhibitory, GABAergic neurons by MRI.

Quantitative evaluation of MRI-based tracking of ferritin-labeled endogenous neural stem cell progeny in rodent brain.

Magnetically triggered clustering of biotinylated iron oxide nanoparticles in the presence of streptavidinylated enzymes.

Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model.

Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography.

In situ labeling and imaging of endogenous neural stem cell proliferation and migration.

Hierarchical non-negative matrix factorization (hNMF): a tissue pattern differentiation method for glioblastoma multiforme diagnosis using MRSI.

Reproducibility of rapid short echo time CSI at 3 tesla for clinical applications.

Mapping of oxygen by imaging lipids relaxation enhancement: A potential sensitive endogenous MRI contrast to map variations in tissue oxygenation.

A single-dose toxicity study on non-radioactive iodinated hypericin for a targeted anticancer therapy in mice.

Exploring theranostic potentials of radioiodinated hypericin in rodent necrosis models.

Unsupervised nosologic imaging for glioma diagnosis.

Does rosiglitazone affect adiposity and cardiac function in genetic diabetic mice?

Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes.

Diabetes mellitus and the metabolic syndrome do not abolish, but might reduce, the cardioprotective effect of ischemic postconditioning.

Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and ¹⁹F-MRI tracking of dendritic cells.

2-D strain assessment in the mouse through spatial compounding of myocardial velocity data: in vivo feasibility.

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

Towards non-invasive monitoring of pathogen-host interactions during Candida albicans biofilm formation using in vivo bioluminescence.

Magnetic layer-by-layer coated particles for efficient MRI of dendritic cells and mesenchymal stem cells.

A pictorial essay on fetal rabbit anatomy using micro-ultrasound and magnetic resonance imaging.

Bioluminescence imaging of fungal biofilm development in live animals.

In vivo hepatocyte MR imaging using lactose functionalized magnetoliposomes.

Sensitive in vivo cell detection using size-optimized superparamagnetic nanoparticles.

Reporter gene approaches for mapping cell fate decisions by MRI: promises and pitfalls.

Variability in contrast agent uptake by different but similar stem cell types.

Integrating diffusion kurtosis imaging, dynamic susceptibility-weighted contrast-enhanced MRI, and short echo time chemical shift imaging for grading gliomas.

Synthetic antiferromagnetic nanoparticles as potential contrast agents in MRI.

A role for LHC1 in higher order structure and complement binding of the Cryptococcus neoformans capsule.

Cytotoxicity of cadmium-free quantum dots and their use in cell bioimaging.

Magnetic resonance imaging for noninvasive assessment of lung fibrosis onset and progression: cross-validation and comparison of different magnetic resonance imaging protocols with micro-computed tomography and histology in the bleomycin-induced mouse model.

Bioluminescence imaging of stroke-induced endogenous neural stem cell response.

The performance of gradient alloy quantum dots in cell labeling.

In vivo and ex vivo assessment of the blood brain barrier integrity in different glioblastoma animal models.

Early decrease of type 1 cannabinoid receptor binding and phosphodiesterase 10A activity in vivo in R6/2 Huntington mice.

Controlling and monitoring stem cell safety in vivo in an experimental rodent model.

High-content imaging and gene expression analysis to study cell-nanomaterial interactions: the effect of surface hydrophobicity.

Magnetoliposomes as magnetic resonance imaging contrast agents.

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.

Longitudinal assessment of infarct progression, brain metabolism and behavior following anterior cerebral artery occlusion in rats.

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors.

Enhanced β-adrenergic cardiac reserve in Trpm4-/- mice with ischemic heart failure.

Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice.

Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity.

Visualization of delayed release of compounds from pH-sensitive capsules in vitro and in vivo in a hamster model.

PET imaging of TSPO in a rat model of local neuroinflammation induced by intracerebral injection of lipopolysaccharide.

High content analysis at single cell level identifies different cellular responses dependent on nanomaterial concentrations.

Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach.

Tumour Relapse Prediction Using Multiparametric MR Data Recorded during Follow-Up of GBM Patients.

Hierarchical non-negative matrix factorization to characterize brain tumor heterogeneity using multi-parametric MRI.

Body distribution of SiO₂-Fe₃O₄ core-shell nanoparticles after intravenous injection and intratracheal instillation.

Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung volume.

Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research.

A multifunctional contrast dye for morphological research.

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.

Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors.

Transplacental sildenafil rescues lung abnormalities in the rabbit model of diaphragmatic hernia.

In vivo evidence for long-term vascular remodeling resulting from chronic cerebral hypoperfusion in mice.

Longitudinal, in vivo assessment of invasive pulmonary aspergillosis in mice by computed tomography and magnetic resonance imaging.

Positive Association Between Limbic Metabotropic Glutamate Receptor 5 Availability and Novelty-Seeking Temperament in Humans: An 18F-FPEB PET Study.

Evaluation of quantum dot cytotoxicity: interpretation of nanoparticle concentrations versus intracellular nanoparticle numbers.

Development of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging.

In vivo and ex vivo 19-fluorine magnetic resonance imaging and spectroscopy of beta-cells and pancreatic islets using GLUT-2 specific contrast agents.

Presence of an Immune System Increases Anti-Tumor Effect of Ag Nanoparticle Treated Mice.

Image-based in vivo assessment of targeting accuracy of stereotactic brain surgery in experimental rodent models.

Standard Cellular Testing Conditions Generate an Exaggerated Nanoparticle Cytotoxicity Profile.

Characterization of a rat orthotopic pancreatic head tumor model using three-dimensional and quantitative multi-parametric MRI.

Visualization, Quantification and Characterization of Caerulein-Induced Acute Pancreatitis in Rats by 3.0T Clinical MRI, Biochemistry and Histomorphology.

An advanced MRI and MRSI data fusion scheme for enhancing unsupervised brain tumor differentiation.

Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia.

Classifying Glioblastoma Multiforme Follow-Up Progressive vs. Responsive Forms Using Multi-Parametric MRI Features.

Limiting the protein corona: A successful strategy for in vivo active targeting of anti-HER2 nanobody-functionalized nanostars.

In Silico Design of Optimal Dissolution Kinetics of Fe-Doped ZnO Nanoparticles Results in Cancer-Specific Toxicity in a Preclinical Rodent Model.

No Effect of Dietary Aspartame or Stevia on Pancreatic Acinar Carcinoma Development, Growth, or Induced Mortality in a Murine Model.

Personalized medicine and follow-up of therapeutic delivery through exploitation of quantum dot toxicity.

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma.

No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma.

The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile.

Murine Pancreatic Acinar Cell Carcinoma Growth Kinetics Are Independent of Dietary Vitamin D Deficiency or Supplementation.

The successive projection algorithm as an initialization method for brain tumor segmentation using non-negative matrix factorization.

Clinical Metabolomics and Glaucoma.

Micro-HCCs in rats with liver cirrhosis: paradoxical targeting effects with vascular disrupting agent CA4P.

Vascular disrupting agent in pancreatic and hepatic tumour allografts: observations of location-dependent efficacy by MRI, microangiography and histomorphology.

Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.

Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia.

NOD mice, susceptible to pancreatic autoimmunity, demonstrate delayed growth of pancreatic cancer.

Pretargeted PET Imaging Using a Bioorthogonal F-Labeled trans-Cyclooctene in an Ovarian Carcinoma Model.

Nanoparticle-induced inflammation can increase tumor malignancy.

High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease.

Bronchoscopic fibered confocal fluorescence microscopy for longitudinal in vivo assessment of pulmonary fungal infections in free-breathing mice.

Glutamatergic Biomarkers for Cocaine Addiction: A Longitudinal Study Using MR Spectroscopy and mGluR5 PET in Self-Administering Rats.

Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema.

Bioluminescence imaging increases in vivo screening efficiency for antifungal activity against device-associated Candida albicans biofilms.

A Magnetic Chameleon: Biocompatible Lanthanide Fluoride Nanoparticles with Magnetic Field Dependent Tunable Contrast Properties as a Versatile Contrast Agent for Low to Ultrahigh Field MRI and Optical Imaging in Biological Window.

A Multimodal Imaging Approach Enables Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis.

The human somatostatin receptor type 2 as an imaging and suicide reporter gene for pluripotent stem cell-derived therapy of myocardial infarction.

Effects of alcohol exposure on the glutamatergic system: a combined longitudinal F-FPEB and H-MRS study in rats.

Magnetoliposomes as Contrast Agents for Longitudinal in vivo Assessment of Transplanted Pancreatic Islets in a Diabetic Rat Model.

Cartilage-on-cartilage contact: effect of compressive loading on tissue deformations and structural integrity of bovine articular cartilage.

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.

Functional assessment of strains around a full-thickness and critical sized articular cartilage defect under compressive loading using MRI.

Non-invasive assessment of disease progression and neuroprotective effects of dietary coconut oil supplementation in the ALS SOD1 mouse model: A H-magnetic resonance spectroscopic study.

Monitoring of Fluconazole and Caspofungin Activity against Candida glabrata Biofilms by Bioluminescence Imaging.

Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology.

Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model.

Early neuropathological and neurobehavioral consequences of preterm birth in a rabbit model.

Motor cortex metabolite alterations in amyotrophic lateral sclerosis assessed in vivo using edited and non-edited magnetic resonance spectroscopy.

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis.

Low-Dose Imaging in a New Preclinical Total-Body PET/CT Scanner.

Quantitative Assessment of Age-Associated Alterations in Brain Vasculature in Wild-Type Mice and in Bigenic Mice that Model Alzheimer's Disease.

Sensorimotor cortex neurometabolite levels as correlate of motor performance in normal aging: evidence from a H-MRS study.

Combined enzymatic degradation of proteoglycans and collagen significantly alters intratissue strains in articular cartilage during cyclic compression.

CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression.

Targeting tumor cells and neovascularization using RGD-functionalized magnetoliposomes.

Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis.

Publisher Correction: Early neuropathological and neurobehavioral consequences of preterm birth in a rabbit model.

Development of Superparamagnetic Nanoparticles Coated with Polyacrylic Acid and Aluminum Hydroxide as an Efficient Contrast Agent for Multimodal Imaging.

Proton range verification with ultrasound imaging using injectable radiation sensitive nanodroplets: a feasibility study.

The Added Value of Longitudinal Imaging for Preclinical Efficacy Testing of Therapeutic Compounds against Cerebral Cryptococcosis.

Establishment, Characterization, and Imaging of a First Platinum-resistant Penile Cancer Patient-derived Xenograft in Nude Mice: A eUROGEN Project.

Characterization of a preclinical PET insert in a 7 tesla MRI scanner: beyond NEMA testing.

Simultaneous in vivo PET/MRI using fluorine-18 labeled FeO@Al(OH) nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution.

Non-invasive characterization of amyotrophic lateral sclerosis in a hTDP-43 mouse model: A PET-MR study.

Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility.

Metabolomic profiling of aqueous humor from glaucoma patients - The metabolomics in surgical ophthalmological patients (MISO) study.

Radiation dose-escalation and dose-fractionation modulate the immune microenvironment, cancer stem cells and vasculature in experimental high-grade gliomas.

Assessment of the Theranostic Potential of Gold Nanostars-A Multimodal Imaging and Photothermal Treatment Study.

ViceCT and whiceCT for simultaneous high-resolution visualization of craniofacial, brain and ventricular anatomy from micro-computed tomography.

Trehalose as quantitative biomarker for in vivo diagnosis and treatment follow-up in cryptococcomas.

Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma.

Modulating ultrasound contrast generation from injectable nanodroplets for proton range verification by varying the degree of superheat.

Safety and Homing of Human Dental Pulp Stromal Cells in Head and Neck Cancer.

Contribution of preclinical MRI to responsible animal research: living up to the 3R principle.

CryptoCEST: A promising tool for spatially resolved identification of fungal brain lesions and their differentiation from brain tumors with MRI.

Neurometabolic Correlates of Reactive and Proactive Motor Inhibition in Young and Older Adults: Evidence from Multiple Regional H-MR Spectroscopy.

Clec4e-Receptor Signaling in Myocardial Repair After Ischemia-Reperfusion Injury.

Fluorinated PLGA-PEG-Mannose Nanoparticles for Tumor-Associated Macrophage Detection by Optical Imaging and MRI.

Synthetic Antiferromagnetic Gold Nanoparticles as Bimodal Contrast Agents in MRI and CT-An Experimental In Vitro and In Vivo Study.

Prenatal Radiation Exposure Leads to Higher-Order Telencephalic Dysfunctions in Adult Mice That Coincide with Reduced Synaptic Plasticity and Cerebral Hypersynchrony.

Label-Free Iron Oxide Nanoparticles as Multimodal Contrast Agents in Cells Using Multi-Photon and Magnetic Resonance Imaging.

Fluorine MR Imaging Probes Dynamic Migratory Profiles of Perfluorocarbon-Loaded Dendritic Cells After Streptozotocin-Induced Inflammation.

Myocardial ischemia-reperfusion injury and the influence of inflammation.

Multimodal Imaging of the Integrated Postnatal Development of Brain and Skull and Its Co-modulation With Neurodevelopment in a Down Syndrome Mouse Model.

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.

Arteriovenous Fistulae in Chronic Kidney Disease and the Heart: Physiological, Histological, and Transcriptomic Characterization of a Novel Rat Model.

Magnetic resonance imaging as a non-invasive tool to assess gastric emptying in mice.

Organization of neurochemical interactions in young and older brains as revealed with a network approach: Evidence from proton magnetic resonance spectroscopy (H-MRS).

Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a H-MRS study.

Brain development is altered in rabbit fetuses with congenital diaphragmatic hernia.

N-acetyl-aspartate and Myo-inositol as Markers of White Matter Microstructural Organization in Mild Cognitive Impairment: Evidence from a DTI-H-MRS Pilot Study.

In vivo assessment of differences in fungal cell density in cerebral cryptococcomas of mice infected with Cryptococcus neoformans or Cryptococcus gattii.

A multimodal imaging study to highlight elastin-derived peptide pro-tumoral effect in a pancreatic xenograft model.

Q-VAT: Quantitative Vascular Analysis Tool.

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates.

Targeted STAT1 therapy for LZTR1-driven peripheral nerve sheath tumor.

Preclinical Models for Cryptococcosis of the CNS and Their Characterization Using In Vivo Imaging Techniques.

Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse model.