Catherine K. Yeung

Benzydamine N-oxygenation as a measure of flavin-containing monooxygenase activity.

Prochiral sulfoxidation as a probe for flavin-containing monooxygenases.

Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.

Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylase.

Qualitative analysis of the role of metabolites in inhibitory drug-drug interactions: literature evaluation based on the metabolism and transport drug interaction database.

Are circulating metabolites important in drug-drug interactions?: Quantitative analysis of risk prediction and inhibitory potency.

e-PKGene: a knowledge-based research tool for analysing the impact of genetics on drug exposure.

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport.

Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects.

Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress.

Direct protein-protein interactions and substrate channeling between cellular retinoic acid binding proteins and CYP26B1.

Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients.

Development of a microphysiological model of human kidney proximal tubule function.

Effect of Coenzyme Q on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ Biomarker Trial.

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.

Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Kidneys on Chips: Emerging Technology for Preclinical Drug Development.

A new LC-MS assay for the quantitative analysis of vitamin K metabolites in human urine.

Tissue Chips in Space-Challenges and Opportunities.

"Natural" is not synonymous with "Safe": Toxicity of natural products alone and in combination with pharmaceutical agents.

Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People.

An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion.

Microphysiological system modeling of ochratoxin A-associated nephrotoxicity.

Prediction of Kidney Drug Clearance: A Comparison of Tubular Secretory Clearance and Glomerular Filtration Rate.

Microphysiological systems in absorption, distribution, metabolism, and elimination sciences.

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing.

Analysis of Drug-Drug Interaction Labeling Language and Clinical Recommendations for Newly Approved Drugs Evaluated With Digoxin, Midazolam, and S-Warfarin.

Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.

Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury.

Kidney microphysiological models for nephrotoxicity assessment.

Metabolomic Profiling Identifies New Endogenous Markers of Tubular Secretory Clearance.

Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.

Predicting complex kidney drug handling using a physiologically-based pharmacokinetic model informed by biomarker-estimated secretory clearance and blood flow.

Development of a kidney microphysiological system hardware platform for microgravity studies.

Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system.