Gregory G. Freund

Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta.

IL-10 promotes survival of microglia without activating Akt.

Dual sampling of the endocervix and its impact on AutoCyte Prep endocervical adequacy.

Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor.

Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.

Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts.

New red blood cell lysing fixative for use in fine needle aspiration and fluid cytology.

Effectiveness of the SurePath liquid-based Pap test in automated screening and in detection of HSIL.

IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta.

Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis.

Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.

IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells.

Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide.

Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.

Additional collection devices used in conjunction with the SurePath Liquid-Based Pap Test broom device do not enhance diagnostic utility.

IL-1beta-mediated innate immunity is amplified in the db/db mouse model of type 2 diabetes.

Test performance comparison of inform HPV and hybrid capture 2 high-risk HPV DNA tests using the SurePath liquid-based Pap test as the collection method.

Medical students who decompress during the M-1 year outperform those who fail and repeat it: a study of M-1 students at the University of Illinois College of Medicine at Urbana-Champaign 1988-2000.

Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness.

A reduced carbohydrate, increased protein diet stabilizes glycemic control and minimizes adipose tissue glucose disposal in rats.

C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.

Psychoneuroimmune implications of type 2 diabetes.

Cytokines in type 2 diabetes.

Gender plays no role in student ability to perform on computer-based examinations.

Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK.

Acute hypoxia activates the neuroimmune system, which diabetes exacerbates.

LPS-dependent suppression of social exploration is augmented in type 1 diabetic mice.

Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.

Phagocytosis of cholesteryl ester is amplified in diabetic mouse macrophages and is largely mediated by CD36 and SR-A.

Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNFalpha-induced resistance to IGF-I in myoblasts.

Detection of Chlamydia trachomatis and Neisseria gonorrhoeae infections in North American women by testing SurePath liquid-based Pap specimens in APTIMA assays.

Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system.

Acute hypoxia, diabetes, and neuroimmune dysregulation: converging mechanisms in the brain.

From inflammation to sickness and depression: when the immune system subjugates the brain.

Ca2+/calmodulin-dependent kinase kinase alpha is expressed by monocytic cells and regulates the activation profile.

The implication of proinflammatory cytokines in type 2 diabetes.

Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK.

Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.

Behavioral recovery from acute hypoxia is reliant on leptin.

Accelerated recovery from acute hypoxia in obese mice is due to obesity-associated up-regulation of interleukin-1 receptor antagonist.

Psychoneuroimmunology. Preface.

Psychoneuroimmune implications of type 2 diabetes: redux.

Collection of the BD SurePath Pap Test with a broom device plus endocervical brush improves disease detection when compared to the broom device alone or the spatula plus endocervical brush combination.

Market survey predictions on the future of US Pap testing.

Sickness behavior induced by endotoxin can be mitigated by the dietary soluble fiber, pectin, through up-regulation of IL-4 and Th2 polarization.

Effect of live-fire training drills on firefighters' platelet number and function.

Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.

Acute hypoglycemia causes depressive-like behaviors in mice.

Macrophages make me sick: how macrophage activation states influence sickness behavior.

The biobehavioral and neuroimmune impact of low-dose ionizing radiation.

The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer.

Individually ventilated cages cause chronic low-grade hypoxia impacting mice hematologically and behaviorally.

Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors.

Development of a Lactobacillus specific T-RFLP method to determine lactobacilli diversity in complex samples.

Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.

IL-1 receptor 2 (IL-1R2) and its role in immune regulation.

Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice.

Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice.