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Department of Pathology and Molecule Medicine
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The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2004 | Pubmed ID: 14707090
The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2004 | Pubmed ID: 15004180
Impact of LL-37 on anti-infective immunity.
Journal of leukocyte biology Apr, 2005 | Pubmed ID: 15569695
A re-evaluation of the role of host defence peptides in mammalian immunity.
Current protein & peptide science Feb, 2005 | Pubmed ID: 15638767
Immunomodulatory activities of small host defense peptides.
Antimicrobial agents and chemotherapy May, 2005 | Pubmed ID: 15855488
Anti-endotoxin properties of cationic host defence peptides and proteins.
Journal of endotoxin research , 2005 | Pubmed ID: 16176660
Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37.
American journal of respiratory cell and molecular biology Apr, 2006 | Pubmed ID: 16340000
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16456005
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.
Journal of leukocyte biology Sep, 2006 | Pubmed ID: 16793910
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2006 | Pubmed ID: 17114497
CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells.
Biochemical and biophysical research communications Feb, 2007 | Pubmed ID: 17174274
Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2007 | Pubmed ID: 18025214
Conserved domains of the class A scavenger receptors: evolution and function.
Immunological reviews Jan, 2009 | Pubmed ID: 19120472
MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.
PLoS pathogens Jun, 2009 | Pubmed ID: 19521507
Host defence peptide LL-37 induces IL-6 expression in human bronchial epithelial cells by activation of the NF-kappaB signaling pathway.
Journal of innate immunity , 2009 | Pubmed ID: 20375583
Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia.
Cell host & microbe Sep, 2010 | Pubmed ID: 20833375
The macrophage.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22262440
The evolution of the class A scavenger receptors.
BMC evolutionary biology , 2012 | Pubmed ID: 23181696
MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2013 | Pubmed ID: 23197261
Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer.
Journal of leukocyte biology Apr, 2013 | Pubmed ID: 23341539
Immunosenescence and novel vaccination strategies for the elderly.
Frontiers in immunology , 2013 | Pubmed ID: 23825474
HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2013 | Pubmed ID: 24043886
A Guide to Bioinformatics for Immunologists.
Frontiers in immunology , 2013 | Pubmed ID: 24363654
McMaster University
Alicja Puchta1,
Chris P. Verschoor1,
Tanja Thurn1,
Dawn M. E. Bowdish1
1Department of Pathology and Molecule Medicine, McMaster University
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