Chirlmin Joo

Exploring rare conformational species and ionic effects in DNA Holliday junctions using single-molecule spectroscopy.

Single-molecule three-color FRET.

Repetitive shuttling of a motor protein on DNA.

Analysis of single-molecule FRET trajectories using hidden Markov modeling.

Real-time observation of RecA filament dynamics with single monomer resolution.

Fueling protein DNA interactions inside porous nanocontainers.

Advances in single-molecule fluorescence methods for molecular biology.

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA.

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation.

Single-molecule four-color FRET.

Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation.

Real-time observation of strand exchange reaction with high spatiotemporal resolution.

A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins.

Labeling DNA (or RNA) for single-molecule FRET.

Labeling proteins for single-molecule FRET.

Preparing sample chambers for single-molecule FRET.

Imaging and identifying impurities in single-molecule FRET studies.

Objective-type total internal reflection microscopy (excitation) for single-molecule FRET.

Objective-type total internal reflection microscopy (emission) for single-molecule FRET.

Bringing single-molecule spectroscopy to macromolecular protein complexes.

Prism-type total internal reflection microscopy for single-molecule FRET.

Single-molecule FRET with total internal reflection microscopy.

Molecular mechanism of sequence-dependent stability of RecA filament.