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Nuclear Dynamics Programme
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Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin.
Genomics Feb, 2002 | Pubmed ID: 11829491
Identification of the autoantigen SART-1 as a candidate gene for the development of atopy.
Human molecular genetics Sep, 2002 | Pubmed ID: 12189166
Antisense intergenic transcription in V(D)J recombination.
Nature immunology Jun, 2004 | Pubmed ID: 15107847
Genomic analysis of facioscapulohumeral muscular dystrophy.
Briefings in functional genomics & proteomics Oct, 2003 | Pubmed ID: 15239924
Regulation of IgH gene assembly: role of the intronic enhancer and 5'DQ52 region in targeting DHJH recombination.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2006 | Pubmed ID: 16456003
Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2006 | Pubmed ID: 16547259
Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu.
Molecular and cellular biology Aug, 2007 | Pubmed ID: 17526723
Myc dynamically and preferentially relocates to a transcription factory occupied by Igh.
PLoS biology Aug, 2007 | Pubmed ID: 17622196
Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.
American journal of human genetics Aug, 2007 | Pubmed ID: 17668377
Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice.
The Journal of experimental medicine Dec, 2007 | Pubmed ID: 18086860
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.
Cell Dec, 2008 | Pubmed ID: 19070574
Large-scale chromatin remodeling at the immunoglobulin heavy chain locus: a paradigm for multigene regulation.
Advances in experimental medicine and biology , 2009 | Pubmed ID: 19731801
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
Science signaling , 2010 | Pubmed ID: 20699475
ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.
Cancer cell May, 2011 | Pubmed ID: 21575860
The Babraham Institute
Daniel J. Bolland1,
Michelle R. King2,
Wolf Reik2,3,
Anne E. Corcoran1,
Christel Krueger2
1Nuclear Dynamics Programme, The Babraham Institute,
2Epigenetics Programme, The Babraham Institute,
3Centre for Trophoblast Research, University of Cambridge
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