Stem Cell Research Unit
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Immune cells mimic the morphology of endothelial progenitor colonies in vitro.
Stem cells (Dayton, Ohio) Jul, 2007 | Pubmed ID: 17395771
Humanized system to propagate cord blood-derived multipotent mesenchymal stromal cells for clinical application.
Regenerative medicine Jul, 2007 | Pubmed ID: 17635045
Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.
Transfusion Aug, 2007 | Pubmed ID: 17655588
Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum.
Tissue engineering. Part C, Methods Sep, 2008 | Pubmed ID: 18620484
Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.
Blood Jun, 2009 | Pubmed ID: 19321860
Platelet-derived growth factors for GMP-compliant propagation of mesenchymal stromal cells.
Bio-medical materials and engineering , 2009 | Pubmed ID: 20042793
Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions.
Haematologica Jun, 2010 | Pubmed ID: 20053868
Pro-angiogenic induction of myeloid cells for therapeutic angiogenesis can induce mitogen-activated protein kinase p38-dependent foam cell formation.
Cytotherapy Apr, 2011 | Pubmed ID: 21128706
Human dermis harbors distinct mesenchymal stromal cell subsets.
The Journal of investigative dermatology Mar, 2012 | Pubmed ID: 22048731
Increased Expression of Micro-RNA-23a Mediates Chemoresistance to Cytarabine in Acute Myeloid Leukemia.
Cancers Feb, 2020 | Pubmed ID: 32093419
A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML.
Epigenetics Aug, 2020 | Pubmed ID: 32114880
Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment.
Blood May, 2012 | Pubmed ID: 22490334
Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo.
PloS one , 2012 | Pubmed ID: 22970226
Identification of an effective early signaling signature during neo-vasculogenesis in vivo by ex vivo proteomic profiling.
PloS one , 2013 | Pubmed ID: 23826172
Placental mesenchymal stromal cells derived from blood vessels or avascular tissues: what is the better choice to support endothelial cell function?
Stem cells and development Jan, 2015 | Pubmed ID: 25244528
Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation.
Blood Jan, 2015 | Pubmed ID: 25406351
Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue.
Cytotherapy Feb, 2016 | Pubmed ID: 26669908
Identification of the Human Skeletal Stem Cell.
Cell Sep, 2018 | Pubmed ID: 30241615
High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34-positive AML.
Cancer medicine Apr, 2019 | Pubmed ID: 30848055
TP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse model.
Annals of hematology Mar, 2020 | Pubmed ID: 32002654
Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
American journal of hematology Jun, 2020 | Pubmed ID: 32602117
Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia.
Clinical epigenetics Jan, 2021 | Pubmed ID: 33407852
EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.
Leukemia May, 2021 | Pubmed ID: 33589750
miR-23a mediates resistance to hypomethylating agents in myeloid neoplasms.
Annals of hematology Nov, 2021 | Pubmed ID: 34291333
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi.
Genome research Nov, 2021 | Pubmed ID: 34407984
Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism.
Science advances Jan, 2022 | Pubmed ID: 35061544
Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations.
Annals of hematology Apr, 2022 | Pubmed ID: 35083527
Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody.
EMBO reports Apr, 2022 | Pubmed ID: 35156745
The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.
Blood cancer discovery Jul, 2022 | Pubmed ID: 35532363
Dysregulated Lipid Synthesis by Oncogenic IDH1 Mutation Is a Targetable Synthetic Lethal Vulnerability.
Cancer discovery Feb, 2023 | Pubmed ID: 36355448
Thrombopoietin-independent Megakaryocyte Differentiation of Hematopoietic Progenitor Cells from Patients with Myeloproliferative Neoplasms.
Bio-protocol Jan, 2023 | Pubmed ID: 36789162
Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Leukemia Feb, 2023 | Pubmed ID: 36813992
1Division of Hematology, Department of Internal Medicine, Medical University of Graz,
2Division of Hematology, Stanford Cancer Institute, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine,
3Department of Blood Group Serology and Transfusion Medicine, Medical University of Graz