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Department of Pediatrics
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Identification and characterization of transcription factor target genes using gene-targeted mice.
Methods (San Diego, Calif.) Jan, 2002 | Pubmed ID: 12054905
Characterization of transcriptional regulation during negative selection in vivo.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2003 | Pubmed ID: 12847248
E2F1 and E2F2 are differentially required for homeostasis-driven and antigen-induced T cell proliferation in vivo.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2005 | Pubmed ID: 16002659
Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia.
Blood Sep, 2009 | Pubmed ID: 19643988
Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.
Investigational new drugs Apr, 2012 | Pubmed ID: 21046425
Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus.
PloS one , 2012 | Pubmed ID: 22363695
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.
ACS medicinal chemistry letters Feb, 2012 | Pubmed ID: 22662287
Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission.
Journal of hematology & oncology , 2013 | Pubmed ID: 23343252
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
The Journal of clinical investigation May, 2013 | Pubmed ID: 23585477
UNC1062, a new and potent Mer inhibitor.
European journal of medicinal chemistry Jul, 2013 | Pubmed ID: 23693152
Molecular Pathways: MERTK Signaling in Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2013 | Pubmed ID: 23833304
Mer receptor tyrosine kinase is a therapeutic target in pre-B-cell acute lymphoblastic leukemia.
Blood Aug, 2013 | Pubmed ID: 23861246
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
The Journal of clinical investigation Aug, 2013 | Pubmed ID: 23867499
UNC569, a novel small molecule Mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
Molecular cancer therapeutics Aug, 2013 | Pubmed ID: 23997116
University of Colorado Anschutz Medical Campus
Sandra Christoph1,2,
Alisa B. Lee-Sherick1,
Susan Sather1,
Deborah DeRyckere1,
Douglas K. Graham1
1Department of Pediatrics, University of Colorado Anschutz Medical Campus,
2Department of Bone Marrow Transplantation, University Hospital of Essen
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