Peter D. Burbelo

The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization.

Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships.

Detecting protein-protein interactions using Renilla luciferase fusion proteins.

Structure and function of human Vps20 and Snf7 proteins.

The role of SPECs, small Cdc42-binding proteins, in F-actin accumulation at the immunological synapse.

A simplified immunoprecipitation method for quantitatively measuring antibody responses in clinical sera samples by using mammalian-produced Renilla luciferase-antigen fusion proteins.

Biochemical characterization of distinct regions of SPEC molecules and their role in phagocytosis.

Rapid antibody quantification and generation of whole proteome antibody response profiles using LIPS (luciferase immunoprecipitation systems).

High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome.

Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection.

A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2.

A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection.

Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

Serological diagnosis of human herpes simplex virus type 1 and 2 infections by luciferase immunoprecipitation system assay.

Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection.

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies.

A four-antigen mixture for rapid assessment of Onchocerca volvulus infection.

Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine.

Human antibody titers to Epstein-Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay.

Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome.

Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.

Rapid serological detection of autoantibodies associated with Sjögren's syndrome.

Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta.

High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance.

Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease.

Extraordinary antigenicity of the human Ro52 autoantigen.

Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma.

Antibody-profiling technologies for studying humoral responses to infectious agents.

Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients.

Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia.

Synthetic biology for translational research.

Rapid induction of autoantibodies during ARDS and septic shock.

Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis.

LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV.

Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States.

Emerging tactical strategies for fighting the war on cancer based on the genetic landscape.

Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems.

Antibody profiling of Borrelia burgdorferi infection in horses.

Microfluidic LIPS for serum antibody detection: demonstration of a rapid test for HSV-2 infection.

Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent.

Soluble rhesus lymphocryptovirus gp350 protects against infection and reduces viral loads in animals that become infected with virus after challenge.

The clinical relevance of persistent recombinant immunoblot assay-indeterminate reactions: insights into the natural history of hepatitis C virus infection and implications for donor counseling.