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Department of Pediatrics
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Shiga toxin interactions with the intestinal epithelium.
Methods in molecular medicine , 2003 | Pubmed ID: 12375435
Molecular and functional analysis of glutamine uptake in human hepatoma and liver-derived cells.
American journal of physiology. Gastrointestinal and liver physiology Nov, 2002 | Pubmed ID: 12381519
Translating tissue culture results into animal models: the case of Salmonella typhimurium.
Trends in microbiology Dec, 2003 | Pubmed ID: 14659688
Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia.
Proceedings of the National Academy of Sciences of the United States of America May, 2004 | Pubmed ID: 15123795
Intestinal epithelial defense systems protect against bacterial threats.
Current gastroenterology reports Oct, 2004 | Pubmed ID: 15341710
Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrhea.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Sep, 2004 | Pubmed ID: 15356801
Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2004 | Pubmed ID: 15494523
Involvement of phospholipase A2 in Pseudomonas aeruginosa-mediated PMN transepithelial migration.
American journal of physiology. Lung cellular and molecular physiology Apr, 2006 | Pubmed ID: 16272174
Salmonella enterica serovar Typhimurium regulates intercellular junction proteins and facilitates transepithelial neutrophil and bacterial passage.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2007 | Pubmed ID: 17615177
Multiple roles of phospholipase A2 during lung infection and inflammation.
Infection and immunity Jun, 2008 | Pubmed ID: 18411286
Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils.
Infection and immunity Aug, 2008 | Pubmed ID: 18505810
The two-component sensor response regulator RoxS/RoxR plays a role in Pseudomonas aeruginosa interactions with airway epithelial cells.
Microbes and infection / Institut Pasteur Mar, 2010 | Pubmed ID: 19961952
Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells.
American journal of physiology. Lung cellular and molecular physiology Feb, 2011 | Pubmed ID: 21097525
Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2012 | Pubmed ID: 23045615
Role of antilipopolysaccharide antibodies in serum bactericidal activity against Salmonella enterica serovar Typhimurium in healthy adults and children in the United States.
Clinical and vaccine immunology : CVI Oct, 2013 | Pubmed ID: 23803904
Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2013 | Pubmed ID: 24089193
Harvard Medical School
Massachusetts General Hospital
Mark E. Kusek1,2,3,
Michael A. Pazos1,3,
Waheed Pirzai3,
Bryan P. Hurley1,3
1Department of Pediatrics, Harvard Medical School,
2Department of Pediatric Gastroenterology, MGH for Children,
3Mucosal Immunology and Biology Research Center, Massachusetts General Hospital
Eliana Drenkard*,1,
Rhianna M. Hibbler*,1,
D. Alina Gutu2,
Alexander D. Eaton1,
Amy L. Silverio1,
Frederick M. Ausubel2,3,
Bryan P. Hurley1,4,
Lael M. Yonker1,4
1Department of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital,
2Department of Molecular Biology, Massachusetts General Hospital,
3Department of Genetics, Harvard Medical School,
4Department of Pediatrics, Harvard Medical School
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