Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood ClotsRuihao Li 1,2, Zuoguan Chen 1, Yaming Guo 1,2, Changduo Wang 3, Yongpeng Diao 1, Jing Yang 3, Yongjun Li 1,2
1Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, 2Graduate School of Chinese Academy of Medical Sciences & Peking Union Medical College, 3Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical College
A detailed methodology for establishing a minimally invasive rat model of pulmonary embolism using autologous blood clots is described. Additional methods for quantifying the infarcted area and visualizing the pulmonary arterial tree are also provided.
