Mechanistic Insights into Salidroside's Mitochondrial Protection via AMPK/Sirt1/HIF-1α Pathway in Hypoxic HT22 CellsXiaobo Wang 1,2,3, Yatng Zhang 1, Ya Hou 1, Hong Jiang 1, Tingting Kuang 1, Rui Li 3, Xianli Meng 1,2,3
1School of Pharmacy/School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, 2Innovative Institute of Chinese Medicine and Pharmacy/Academy for Interdiscipline, Chengdu University of Traditional Chinese Medicine, 3Research Service Office, Traditional Chinese Medicine Hospital of Meishan
The present study identified a unique mechanism by which salidroside exerts mitochondrial protective effects on hypoxic HT22 cells, partly through the AMPK/Sirt1/HIF-1α pathway.
