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University of California at Irvine

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Generation of Alginate Microspheres for Biomedical Applications
Omaditya Khanna 1, Jeffery C. Larson 2, Monica L. Moya 3, Emmanuel C. Opara 4, Eric M. Brey 2,5
1Department of Chemical and Biological Engineering, Illinois Institute of Technology, 2Department of Biomedical Engineering, Illinois Institute of Technology, 3Department of Biomedical Engineering, University of California at Irvine, 4Wake Forest Institute for Regenerative Medicine and Department of Biomedical Engineering, Wake Forest University Health Sciences, 5Research Service, Hines Veterans Administration Hospital

In the following sections, we outline procedures for the preparation of alginate microspheres for use in biomedical applications. We specifically illustrate a technique for creating multilayered alginate microspheres for the dual purpose of cell and protein encapsulation as a potential treatment for type 1 diabetes.

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