S'identifier

Children's Hospital of Nanjing Medical University

2 ARTICLES PUBLISHED IN JoVE

Behavior

A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice

Ran You^1,2,3, Yan Liu³, Raymond Chuen-Chung Chang³

¹Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, ²Nanjing Key Laboratory of Pediatrics, Nanjing Medical University, ³Laboratory of Neurodegenerative Disease, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region (HK SAR)

A comprehensive behavioral test battery of motor skills, mood—including social interaction, depression, and anxiety—and cognition is designed for the repeated assessment of neurodegeneration-related behavioral changes in mice.

Medicine

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Xiaodong Zang^*1, Di Yu^*1, Zhaocong Yang¹, Qinghui Hu¹, Peicheng Ding¹, Feng Chen¹, Xuming Mo¹

¹Department of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University

The distinct effects of different degrees of hypothermia on myocardial protection have not been thoroughly evaluated. The goal of the present study was to quantify the levels of cell death following different hypothermia treatments in a human cardiomyocyte-based model, laying the foundation for future in-depth molecular research.