Targeting of Deep Brain Structures with Microinjections for Delivery of Drugs, Viral Vectors, or Cell TransplantsOscar Gonzalez-Perez 1, Hugo Guerrero-Cazares 2, Alfredo Quiñones-Hinojosa 2
1 Neuroscience Lab/ Fac. Psicologia, University of Colima, 2Department of Neurosurgery, Johns Hopkins University
In this article, we show a method to make glass capillary needles with a 50-μm lumen. This technique significantly reduces the brain damage, minimizes passive diffusion of drugs and allows a precise targeting into the rodent brain.
