Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow TechnologyChristopher Thornton 1, Gemma Johnson 2, Samir Agrawal 3
1Biosciences, University of Exeter, 2BICMS, Queen Mary University of London, 3St. Bartholomew's Hospital and The London NHS Trust
A rapid and accurate point-of-care test for invasive pulmonary aspergillosis is presented. It takes advantage of lateral-flow technology using a specific monoclonal antibody that binds to an Aspergillus antigen secreted during pulmonary infections. The assay is compatible with serum and brochoalveolar lavage and represents a novel adjunct test for disease diagnosis.
