Clinical Research Institute of Montreal
2 ARTICLES PUBLISHED IN JoVE
Medicine
Mouse Model of Intraluminal MCAO: Cerebral Infarct Evaluation by Cresyl Violet Staining
Estelle Rousselet 1, Jasna Kriz 2, Nabil G. Seidah 1
1Laboratory of Biochemical Neuroendocrinology, Clinical Research Institute of Montreal, 2CHUQ Research Centre, Laval University
The intraluminal middle cerebral occlusion model in mice is herein presented. The extent of cerebral infarct is evaluated by a neurologic score and cresyl violet staining, an alternative staining to TTC, offering the great advantage to test in parallel many interest markers.
Medicine
In utero Measurement of Heart Rate in Mouse by Noninvasive M-mode Echocardiography
WooJin Kim 1, Nabil G. Seidah 1, Annik Prat 1
1Laboratory of Biochemical Neuroendocrinology, Institut de Recherches Cliniques de Montréal
Ultra-high frequency ultrasound is a powerful live imaging tool to examine cardiac abnormalities in small animals. Its noninvasiveness allows maintaining the physiologic state of embryos. Herein, we show the use of M-mode ultrasound to measure the heart rates of embryos at E18.5 in utero.
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