Generation of a Humanized Mouse Liver Using Human Hepatic Stem CellsRan-Ran Zhang *1, Yun-Wen Zheng *1,2,3, Hideki Taniguchi 1
1Department of Regenerative Medicine, Graduate School of Medicine, Yokohama City University, 2Department of Advanced Gastroenterological Surgical Science and Technology, Faculty of Medicine, University of Tsukuba, 3Regenerative Medicine Research Center, Jiangsu University Hospital
Here, we present a novel humanized mouse liver model generated in Alb-toxin receptor mediated cell knockout (TRECK)/SCID mice following the transplantation of immature and expandable human hepatic stem cells.
