Screening Ion Channels in Cancer CellsLaura Kallay 1, Vaibhavkumar S. Gawali 1, Donatien Kamdem Toukam 1, Debanjan Bhattacharya 1, Andrew Jenkins 2, Soma Sengupta 3, Daniel A. Pomeranz Krummel 3
1Department of Neurology and Rehabilitation Medicine, Division of Neuro-Oncology, University of Cincinnati College of Medicine, 2Department of Pharmaceutical Sciences, School of Pharmacy, University of Saint Joseph, 3The Vontz Center for Molecular Studies, University of Cincinnati College of Medicine
The pharmacological targeting of ion channels is a promising approach to treating solid tumors. Detailed protocols are provided for characterizing ion channel function in cancer cells and assaying the effects of ion channel modulators on cancer viability.