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Bioengineering

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds
Bharat Kumar Reddy Sanapalli 1, Kalaivani Chinna Gounder 1, Nilesh Sudhakar Ambhore 2, Gowthamarajan Kuppuswamy 1, Praveen Thaggikuppe Krishnamurthy 3, Veera Venkata Satyanarayana Reddy Karri 1
1Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, 2Department of Pharmaceutical Sciences, School of Pharmacy, North Dakota state university, 3Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research

The prepared DOX-CL scaffold satisfied the prerequisites of an ideal DW dressing in mechanical strength, porosity, water absorption, degradation rate, sustained release, anti-bacterial, biocompatibility, and anti-inflammatory properties, which are considered to be essential for the recovery of damaged tissue in DWs.

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