Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy CharacterizationsXin Dai 1,2, Wenting Qiu 1,2, Jinqing Huang 1,2
1HKUST-Shenzhen Research Institute, 2Department of Chemistry, The Hong Kong University of Science and Technology
The present protocol describes a convenient approach to integrating optical trapping and surface-enhanced Raman spectroscopy (SERS) to manipulate plasmonic nanoparticles for sensitive molecular detection. Without aggregating agents, the trapping laser assembles plasmonic nanoparticles to enhance the SERS signals of target analytes for in situ spectroscopic measurements.
