Sharon Y.R. Dent

Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo.

Transcriptional control: an activating role for arginine methylation.

Site-specific loss of acetylation upon phosphorylation of histone H3.

Physical and functional interaction of the yeast corepressor Tup1 with mRNA 5'-triphosphatase.

c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.

Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation.

Histone modifications in corepressor functions.

GCN5 and p300 share essential functions during early embryogenesis.

The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation.

Histone modifying enzymes and cancer: going beyond histones.

The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation.

No Spt6, no nucleosomes, no activator required.

Functions of histone-modifying enzymes in development.

Transcriptional repression by Tup1-Ssn6.

Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos.

Developmental potential of Gcn5(-/-) embryonic stem cells in vivo and in vitro.

A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.

Cross-regulation of histone modifications.

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.

Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo.

Proper Gcn5 histone acetyltransferase expression is required for normal anteroposterior patterning of the mouse skeleton.

The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin.

The H2BK123Rgument.

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.

R loops stimulate genetic instability of CTG.CAG repeats.

Multiple faces of the SAGA complex.

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes.

Ubp8 and SAGA regulate Snf1 AMP kinase activity.

Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia.

USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1.

Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination.

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.